50549-48-9Relevant academic research and scientific papers
Intervention in cyclophosphamide induced oxidative stress and DNA damage by a flavonyl-thiazolidinedione based organoselenocyanate and evaluation of its efficacy during adjuvant therapy in tumor bearing mice
Roy, Somnath Singha,Chakraborty, Pramita,Bhattacharya, Sudin
, p. 195 - 209 (2014/01/23)
A novel flavonyl-thiazolidinedione based organoselenocyanate compound was synthesized and established as nontoxic at the doses of 2.5 and 5 mg/kg b.w. in mice. Oral administration of the compound in combination with cyclophosphamide (CP) resulted in an im
Synthesis and biological activity of some new flavonyl-2,4-thiazolidinediones
Bozdag-Duendar, Oya,Verspohl, Eugen J.,Das-Evcimen, Net,Kaup, Rebecca M.,Bauer, Katrin,Sarikaya, Mutlu,Evranos, Beguem,Ertan, Rahmiye
, p. 6747 - 6751 (2008/12/23)
A new series of flavonyl-2,4-thiazolidinediones (Va-c, VIa-c) was prepared by Knoevenagel reaction. The synthesized compounds were tested for their ability to inhibit rat kidney aldose reductase (AR) and for their insulinotropic activities in INS-1 cells.
Synthesis and hypoglycemic activity of some new flavone derivatives: 4th communication: 6-flavonyl-2,4-thiazolidinediones
Bozdag-Duendar,Waheed,Verspohl,Ertan
, p. 623 - 627 (2007/10/03)
A new series of flavonyl compounds (1-10) was prepared and tested for their insulinotropic activities in INS-1 cells. Compounds 2, 5 and 6 (at higher concentrations) and compounds 3 and 7-10 were able to increase insulin release in the presence of 5.6 mmo
Unsymmetrical Bichromonyl Benzene Derivatives from Formyl Flavones
Wurm, Gotthard,Nordmann, Matthias
, p. 555 - 558 (2007/10/02)
New flavones (4b-f/6) with formyl functions in the 3-, 4'-, 6- and 4',6-positions are synthesized from bromomethyl or dibromomethyl flavone derivatives (3a-e) with methylflavones (2a-e) as starting compounds.The formyl flavones are suitable synthetic tool
