50563-24-1

Upstream product

• 50563-30-9 methyl 7,9-dibromo-8-oxo-1-oxa-2-azaspiro<4.5>deca-2,6,9-trien-3-carboxylate 
• 50563-23-0 methyl-[2-hydroxyimino-3-(4-hydroxyphenyl)]propionate 
• 58960-71-7 N-[(1,1-dimethylethoxy)carbonyl]-3,5-dibromo-L-tyrosine 
• 355857-30-6 (+)-(S)-methyl 3-(3,5-dibromo-4-hydroxyphenyl)-2-(2-methylprop-2-yloxycarbamoyl)propanoate 
• 1357361-41-1 (+)-(S)-methyl 3-(4-benzyloxy-3,5-dibromophenyl)-2-(2-methylprop-2-yloxycarbamoyl)propanoate 
• 156-39-8 4-hydroxyphenylpiruvic acid 
• 1080-06-4 tyrosine methyl ester 
• 1357361-42-2 (+)-(S)-methyl 2-amino-3-(4-benzyloxy-3,5-dibromophenyl)propanoate 

Downstream Products

• 58511-69-6 3-(3,5-dibromo-4-hydroxyphenyl)-2-(hydroxyimino)propionic acid 

Relevant academic research and scientific papers

Cyclic versus hemi-bastadins. Pleiotropic anti-cancer effects: From apoptosis to anti-angiogenic and anti-migratory effects

Bastadins-6, -9 and -16 isolated from the marine sponge Ianthella basta displayed in vitro cytostatic and/or cytotoxic effects in six human and mouse cancer cell lines. The in vitro growth inhibitory effects of these bastadins were similar in cancer cell

Efficient total synthesis of bastadin 6, an anti-angiogenic brominated tyrosine-derived metabolite from marine sponge

An efficient total synthesis of bastadin 6 (1), a cyclic tetramer of brominated tyrosine derivatives from the marine sponge, Ianthella basta, with selective anti-angiogenic activity, was accomplished. We developed a novel Ce(IV)-mediated oxidative couplin