50622-51-0 Usage
Uses
Used in Pharmaceutical Industry:
N-(4-fluorophenyl)ethylenediamine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with unique therapeutic properties. Its structural features allow for the creation of molecules with specific biological activities, potentially leading to the discovery of novel treatments for various diseases.
Used in Organic Synthesis:
In the field of organic synthesis, N-(4-fluorophenyl)ethylenediamine serves as a versatile building block for the creation of a wide range of organic compounds. Its reactivity and structural characteristics facilitate the formation of complex molecules with diverse applications in various industries.
Used in Dye and Pigment Production:
N-(4-fluorophenyl)ethylenediamine is utilized as a starting material in the production of various dyes and pigments. Its chemical properties enable the development of colorants with specific characteristics, such as color intensity, stability, and solubility, which are essential for applications in textiles, plastics, and other industries.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, N-(4-fluorophenyl)ethylenediamine is employed as a research compound for exploring its potential in drug development. Its unique structure and biological activities make it a promising candidate for the design and synthesis of new pharmaceutical agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 50622-51-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,6,2 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 50622-51:
(7*5)+(6*0)+(5*6)+(4*2)+(3*2)+(2*5)+(1*1)=90
90 % 10 = 0
So 50622-51-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H11FN2/c9-7-1-3-8(4-2-7)11-6-5-10/h1-4,11H,5-6,10H2
50622-51-0Relevant academic research and scientific papers
Design, synthesis and antimycobacterial activity of novel imidazo[1,2-a]pyridine-3-carboxamide derivatives
Lv, Kai,Li, Linhu,Wang, Bo,Liu, Mingliang,Wang, Bin,Shen, Weiyi,Guo, Huiyuan,Lu, Yu
, p. 117 - 125 (2017/06/05)
We report herein the design and synthesis of “novel imidazo [1,2-a]pyridine-3-carboxamides (IPAs)” bearing a variety of different linkers, based on the structure of IMB-1402 discovered in our lab. Results reveal that 2,6-dimethyl-N-[2-(phenylamino)ethyl] IPAs with an electron-donating group on the benzene ring as a potent scaffold. Compounds 26g and 26h have considerable activity (MIC: 0.041–2.64 μM) against drug-sensitive/resistant MTB strains, and they have acceptable safety indices against MTB H37Rv with the SI values of 4395 and 1405, respectively. Moreover, N-[2-(piperazin-1-yl)ethyl] moiety was also identified as a potentially alternative linker (compound 31), opening a new direction for further SAR studies.
FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF
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Paragraph 804; 805, (2016/09/15)
This disclosure is related to a fused-ring compound of formula (I) and/or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the fused ring compound of formula (I) and/or a pharmaceutically acceptable salt thereof, preparation methods thereof, and use thereof in modulating activity of indoleamine 2, 3-dioxygenase (IDO) and/or tryptophan 2, 3-dioxygenase (TDO). This disclosure further provides methods of treating IDO and/or TDO-associated diseases, including cancer, viral infection and autoimmune diseases.
