N-(4-Fluorophenyl)ethylenediamine

Base Information

Chemical Name:N-(4-Fluorophenyl)ethylenediamine
CAS No.:50622-51-0
Molecular Formula:C₈H₁₁FN₂
Molecular Weight:154.187
Hs Code.:
European Community (EC) Number:256-660-7
UNII:YQ478FYJ9C
DSSTox Substance ID:DTXSID10198669
Nikkaji Number:J261.562B
Wikidata:Q83071496
Mol file:50622-51-0.mol

Synonyms:50622-51-0;N-(4-Fluorophenyl)ethylenediamine;N1-(4-Fluorophenyl)ethane-1,2-diamine;N'-(4-fluorophenyl)ethane-1,2-diamine;N-(4-FLUORO-PHENYL)-ETHANE-1,2-DIAMINE;EINECS 256-660-7;YQ478FYJ9C;N-(4-Fluorophenyl)ethane-1,2-diamine;N1-(4-Fluorophenyl)-1,2-ethanediamine;N*1*-(4-Fluoro-phenyl)-ethane-1,2-diamine;UNII-YQ478FYJ9C;SCHEMBL3005414;DTXSID10198669;CSGVXMPCKSSCSY-UHFFFAOYSA-N;N-(2-Aminoethyl)-4-fluoroaniline;MFCD00025596;AKOS011794629;N-(4-Fluorophenyl)-1,2-ethanediamine;SB37411;AM100890;n1-(4-fluoro-phenyl)-ethane-1,2-diamine;1,2-Ethanediamine, N1-(4-fluorophenyl)-;CS-0319960;F79571

Suppliers and Price of N-(4-Fluorophenyl)ethylenediamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N1-(4-Fluorophenyl)-1,2-ethanediamine
50mg
$ 45.00

TRC
N1-(4-Fluorophenyl)-1,2-ethanediamine
500mg
$ 285.00

SynQuest Laboratories
N-(2-Aminoethyl)-4-fluoroaniline 97%
250 mg
$ 143.00

J&W Pharmlab
N-(4-Fluoro-phenyl)-ethane-1,2-diamine 97%
50mg
$ 117.00

Crysdot
N1-(4-Fluorophenyl)ethane-1,2-diamine 95+%
5g
$ 671.00

American Custom Chemicals Corporation
N-(4-FLUOROPHENYL)ETHYLENEDIAMINE 95.00%
5MG
$ 505.29

Alichem
N1-(4-Fluorophenyl)ethane-1,2-diamine
1g
$ 400.00

Acrotein
N1-(4-Fluorophenyl)-1,2-ethanediamine 97%
1g
$ 297.92

Total 12 raw suppliers

Chemical Property of N-(4-Fluorophenyl)ethylenediamine

Chemical Property:

Vapor Pressure:0.0066mmHg at 25°C
Boiling Point:271.1°C at 760 mmHg
Flash Point:117.7°C
PSA：38.05000
Density:1.156g/cm³
LogP:1.96960
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:154.09062652
Heavy Atom Count:11
Complexity:100

Purity/Quality:

97% ^*data from raw suppliers

N1-(4-Fluorophenyl)-1,2-ethanediamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NCCN)F

Technology Process of N-(4-Fluorophenyl)ethylenediamine

There total 2 articles about N-(4-Fluorophenyl)ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 352-34-1
4-fluoro-1-iodobenzene

: 107-15-3,85404-18-8
ethylenediamine

: 50622-51-0
N₁-(4-fluorophenyl)ethane-1,2-diamine

Guidance literature:: With copper(II) oxide; In acetonitrile; at 83 ℃; for 20h;

Reference yield:

: 2576-47-8
2-bromoethylamine hydrobromide

: 371-40-4
4-fluoroaniline

: 50622-51-0
N₁-(4-fluorophenyl)ethane-1,2-diamine

Guidance literature:: In toluene; for 5h; Reflux;
DOI:10.1016/j.ejmech.2017.05.044

Reference yield:

: 50622-51-0
N₁-(4-fluorophenyl)ethane-1,2-diamine

: 849670-38-8
3-(R)-cyclohexylmethyl-N-[2-(4-fluoro-phenylamino)-ethyl]-4-morpholin-4-yl-4-oxo-butyramide

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 5 h

2: lithium hydroxide; water / methanol / 8 h / 0 - 23 °C

3: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane

With lithium hydroxide; water; N-ethyl-N,N-diisopropylamine; HATU; In methanol; dichloromethane;