50666-95-0

Basic information

• Product Name: Benzene, 1-(phenylmethoxy)-4-(2-propenyloxy)-
• CAS NO: 50666-95-0
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Mol File: 50666-95-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(phenylmethoxy)-4-(2-propenyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(phenylmethoxy)-4-(2-propenyloxy)-(50666-95-0)
• EPA Substance Registry System: Benzene, 1-(phenylmethoxy)-4-(2-propenyloxy)-(50666-95-0)

Safety Data

• Hazardous Substances Data: 50666-95-0(Hazardous Substances Data)

Upstream product

• 37592-20-4 1,4-bis(allyloxy)benzene 
• 100-39-0 benzyl bromide 
• 123-31-9 hydroquinone 
• 153164-85-3 1-allyloxy-4-prop-2-ynyloxy-benzene 
• 6411-34-3 4-allyloxyphenol 
• 103-16-2 4-Benzyloxyphenol 
• 106-95-6 allyl bromide 

Downstream Products

• 2170388-84-6 glabralide B 
• 944804-58-4 rhuscholide A 
• 208842-03-9 (RS)-5-benzyloxy-2-bromomethyl-2,3-dihydro-benzofuran 

Relevant articles and documents

Nickel-catalyzed deallylation of aryl allyl ethers with hydrosilanes

An efficient and mild catalytic deallylation method of aryl allyl ethers is developed, with commercially available Ni(COD)2 as catalyst precursor, simple substituted bipyridine as ligand and air-stable hydrosilanes. The process is compatible with a variety of functional groups and the desired phenol products can be obtained with excellent yields and selectivity. Besides, by detection or isolation of key intermediates, mechanism studies confirm that the deallylation undergoes η3-allylnickel intermediate pathway.

Selective cleavage of allyl and propargyl ethers to alcohols catalyzed by Ti(O-i-Pr)4/MXn/Mg

(Chemical Equation Presented) Allyl and propargyl ethers were effectively deallylated or depropargylated to the parent alcohols via a C-O bond cleavage catalyzed by a low-valent titanium reagent (LVT), Ti(O-i-Pr)4/TMSCI/ Mg or Ti(O-i-Pr)4/MgBr2/Mg, under mild reaction conditions. Differentiation between the allyl and propargyl ethers was achieved by the reaction in the presence of AcOEt as an additive. The reagent also catalyzed intra- and intermolecular cyclotrimerization reactions of alkynes to substituted benzenes.

4-hydroxy-piperidine derivatives

The present invention relates to 4-hydroxy-piperidine derivatives of the general formula wherein X denotes —O—, —NH—, —CH2—, —CH═, —CHOH—, —CO—, —S—, —SO— or —SO2—; R1-R4are, independently from each other, hydrogen, hydroxy, lower-alkyl-sulfonylamino, 1- or 2-imidazolyl or acetamido; R5-R8are, independently from each other, hydrogen, hydroxy, lower-alkyl, halogen, lower-alkoxy, trifluoromethyl or trifluoromethyloxy; a and b may be a double bond, provided that when “a” is a double bond, “b” cannot be a double bond; n is 0-2; m is 1-3; p is 0 or 1 and to pharmaceutically acceptable addition salts thereof. Compounds of the present invention are NMDA(N-methyl-D-aspartate)-receptor subtype selective blockers, which can be used in mediating processes underlying development of CNS including learning and memory formation and function.