5082-82-6

Basic information

• Product Name: thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione
• Synonyms: thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione;THIAZOLO[5,4-D]PYRIMIDINE-5,7-DIOL
• CAS NO: 5082-82-6
• Molecular Formula: C₅H₃N₃O₂S
• Molecular Weight: 169.16
• Mol File: 5082-82-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.626
• Refractive Index: 1.635
• Storage Temp.: 2-8°C
• CAS DataBase Reference: thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione(5082-82-6)
• EPA Substance Registry System: thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione(5082-82-6)

Safety Data

• Hazardous Substances Data: 5082-82-6(Hazardous Substances Data)

Usage

General Description

Thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione is a chemical compound with a unique heterocyclic structure containing a thiazole and pyrimidine ring. It is a derivative of the pyrimidine-5,7(4H,6H)-dione family and has potential pharmacological properties. thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione has been studied for its potential as an anti-cancer agent, as well as for its anti-inflammatory and antimicrobial activities. Thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione has also been used as a building block in the synthesis of various bioactive compounds and pharmaceuticals due to its versatile reactivity and potential therapeutic applications. Further research on this compound and its derivatives may lead to the development of new drugs with improved efficacy and reduced side effects.

InChI:InChI=1/C5H3N3O2S/c9-3-2-4(11-1-6-2)8-5(10)7-3/h1H,(H2,7,8,9,10)

Upstream product

• 5021-69-2 (4-carbamoylthiazol-5-yl)carbamic acid ethyl ester 
• 64-18-6 formic acid 
• 34771-17-0 5-amino-4-thio-barbituric acid 

Downstream Products

• 1542704-23-3 N-benzyl-5-(2-methoxy-1H-benzo[d]imidazol-1-yl)thiazolo[5,4-d]pyrimidin-7-amine 
• 1542711-02-3 N-benzyl-5-chlorothiazolo[5,4-d]pyrimidin-7-amine 
• 1542711-03-4 C₁₈H₁₆N₆S 
• 13479-88-4 5,7-dichloro-[1,3]thiazolo[5,4-d]pyrimidine 
• 35867-91-5 4-β-D-ribofuranosyl-4H-thiazolo[5,4-d]pyrimidine-5,7-dione 
• 55520-52-0 7-thioxo-4,6-bis-(tri-O-benzoyl-β-D-ribofuranosyl)-6,7-dihydro-4H-thiazolo[5,4-d]pyrimidin-5-one 
• 55520-48-4 7-methylsulfanyl-4-(tri-O-benzoyl-β-D-ribofuranosyl)-4H-thiazolo[5,4-d]pyrimidin-5-one 
• 55520-46-2 7-thioxo-4-(tri-O-benzoyl-β-D-ribofuranosyl)-6,7-dihydro-4H-thiazolo[5,4-d]pyrimidin-5-one 
• 55520-47-3 7-amino-4-β-D-ribofuranosyl-4H-thiazolo[5,4-d]pyrimidin-5-one 
• 55520-41-7 4-(tri-O-benzoyl-α-D-ribofuranosyl)-4H-thiazolo[5,4-d]pyrimidine-5,7-dione 
• 35867-92-6 4-(tri-O-benzoyl-β-D-ribofuranosyl)-4H-thiazolo[5,4-d]pyrimidine-5,7-dione 
• 55520-49-5 6-(tri-O-benzoyl-β-D-ribofuranosyl)-4H-thiazolo[5,4-d]pyrimidine-5,7-dione 

Relevant articles and documents

IRAK INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Convenient synthesis of 5,7-dichlorothiazolo[5,4-d]pyrimidine

A convenient synthesis of 5,7-dichlorothiazolo[5,4-d]pyrimidine is reported. The condensation of ethyl isocyanoacetate and ethoxycarbonyl isothiocyanate selectively gave the key 5-aminothiazole intermediate in high yield under mild conditions. This interm