50882-16-1Relevant articles and documents
Application of copper(II)-mediated radical cross-dehydrogenative coupling to prepare spirocyclic oxindoles and to a formal total synthesis of Satavaptan
Hurst, Timothy E.,Gorman, Ryan,Drouhin, Pauline,Taylor, Richard J.K.
, p. 6485 - 6496 (2018/10/05)
Application of radical cross-dehydrogenative coupling (CDC) procedures to prepare a range of novel spirocyclic oxindoles and to a formal total synthesis of the vasopressin V2 receptor antagonist Satavaptan is reported. The key step involves a c
Synthesis of potent, substituted carbazoles as selective androgen receptor modulators (SARMs)
Miller, Chris P.,Bhaket, Pushpal,Muthukaman, Nagarajan,Lyttle, C. Richard,Shomali, Maysoun,Gallacher, Kyla,Slocum, Connie,Hattersley, Gary
scheme or table, p. 7516 - 7520 (2011/02/16)
The synthesis and in vitro binding affinity for a novel series of potent androgen receptor modulators is described. One of the more potent compounds (17, RAD35010) was further characterized in vivo where it restored levator ani weight in castrated male ra
The 2-oxocyclopentanecarboxylic acid keto-enol system in aqueous solution: Generation of the enol by hydration of an acylketene
Chiang,Kresge,Nikolaev,Popik
, p. 11183 - 11190 (2007/10/03)
Flash photolysis of 2-diazocyclohexane-1,3-dione in aqueous solution produced 2-ketocyclopentylideneketene, which hydrated to the enol of 2-oxocyclopentanecarboxylic acid, and the enol then isomerized to the keto form of the acid. This ketene proved to be