50903-04-3

Basic information

• Product Name: Morpholine, 4-[(4-nitrophenyl)thioxomethyl]-
• CAS NO: 50903-04-3
• Molecular Formula: C11H12N2O3S
• Molecular Weight: 252.294
• Mol File: 50903-04-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-[(4-nitrophenyl)thioxomethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-[(4-nitrophenyl)thioxomethyl]-(50903-04-3)
• EPA Substance Registry System: Morpholine, 4-[(4-nitrophenyl)thioxomethyl]-(50903-04-3)

Safety Data

• Hazardous Substances Data: 50903-04-3(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 3156-41-0 1-nitro-4-(2-nitrovinyl)benzene 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 100-14-1 4-nitrobenzyl chloride 
• 859793-64-9 C₇H₆ClNO₂S 
• 555-16-8 4-nitrobenzaldehdye 
• 2609-49-6 diethyl p-nitrobenzylphosphonate 
• 26798-33-4 (p-nitrophenyl)methanethiol 

Downstream Products

• 5397-76-2 1-morpholin-4-yl-1-(4-nitro-phenyl)-methanone 
• 76226-64-7 4-(p-nitro-α-methylthiobenzylidene)morpholinium iodide 
• 84302-58-9 4-(4-Methoxy-phenyl)-2-(4-nitro-phenyl)-thiazole-5-carbonitrile 
• 1090-82-0 2-(4-nitrophenyl)-5-phenyl-1,3,4-oxadiazole 
• 111997-59-2 2-(4-nitrophenyl)-5-(pyridin-4-yl)-1,3,4-oxadiazole 
• 83431-80-5 2-(2-hydroxyphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole 
• 64274-23-3 4-methyl-N-(morpholino(4-nitrophenyl)methylene)benzensulfonamide 
• 120290-23-5 4-[Methylsulfanyl-(4-nitro-phenyl)-methyl]-morpholine 
• 555-16-8 4-nitrobenzaldehdye 
• 76226-74-9 N-[1-Morpholin-4-yl-1-(4-nitro-phenyl)-meth-(Z)-ylidene]-N'-quinolin-2-yl-hydrazine; hydriodide 

Relevant articles and documents

Metal-free three-component synthesis of thioamides from β-nitrostyrenes, amines and elemental sulfur

A metal-free C[dbnd]C bond cleavage reaction of β-nitrostyrenes in the presence of elemental sulfur and secondary amines/amides is described. Elemental sulfur serves as both a raw material and an oxidant for C[dbnd]C bond cleavage, and secondary amines or amides are both feasible nitrogen sources. Besides mild reaction condition and simple work-up procedure, the method provided thioamides with good to excellent yields.

Sulfated polyborate catalyzed Kindler reaction: a rapid, efficient, and green protocol

A rapid, green, and efficient one-pot, three-component Kindler reaction was developed using a sulfated polyborate catalyst. The method described the reaction of aldehydes, amines/ammonium acetate, and sulfur for the synthesis of thioamides using sulfated polyborate under a solvent free condition at 100?°C. The key features of the present protocol are high yields, short reaction time, easy workup, and recyclability of a catalyst which gives economical as well as ecological rewards. The present method also has an ability to tolerate a variety of functional groups. Graphical abstract: [Figure not available: see fulltext.].

Reactions of Phosphonate Carbanions with Selenium or Sulfur in the Presence of Amines. Synthesis of Seleno- and Thioamides

The reaction of phosphonate carbanions with elemental selenium in the presence of amines afforded the corresponding selenoamides in moderate yields.The reaction of these anions with sulfur also gave thioamides.These reactions might proceed through thio- or selenoaldehyde intermediates.