509072-58-6Relevant academic research and scientific papers
OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS
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Page/Page column 123; 124, (2015/05/19)
This invention pertains generally to treating bacterial infections using organic compounds of Formula I. In certain aspects, the invention pertains to treating infections caused by Gram-negative bacteria. (I) wherein X, Y, R1, R2, R3, R4 and R5 and defined herein.
Reactivity and regiochemical behavior in the solvolysis reactions of (2,2-difluorocyclopyl)methyl tosylates
Battiste, Merle A.,Tian, Feng,Baker, John M.,Bautista, Olivia,Villalobos, Janette,Dolbier Jr., William R.
, p. 39 - 51 (2007/10/03)
The rate constants for acetolysis of (2,2-difluorocyclopropyl)methyl tosylate, and (2,2-difluoro-3-methylcyclopropyl)methyl tosylate at 92°C and of 1-(2,2-difluoropropyl)ethyl tosylate at 42°C are reported and the rectivities and regiochemistries of ring opening of these systems are discussed and compared with expectations based on computational results. The results are discussed in terms of the use of (2,2-difluorocyclopropyl)methyl systems as mechanistic probes.
