51110-25-9

Upstream product

• 75-15-0 carbon disulfide 
• 120413-57-2 C₂₉H₂₆NO₂P 
• 61013-61-4 ethyl 2-azido-3-phenylacrylate 
• 100-52-7 benzaldehyde 
• 105479-98-9 ethyl 2-(acetoxy(phenyl)methyl)acrylate 

Downstream Products

• 33665-13-3 5-benzylidene-3-isobutyl-2-thioxo-imidazolidin-4-one 
• 53865-24-0 5-benzylidene-2-thioxo-3-m-tolyl-imidazolidin-4-one 
• 821781-86-6 3-phenylamino-5-phenylmethylene-2-thioxo-4-imidazolidinone 
• 1228693-71-7 (S)-2-(4-benzylidene-5-oxo-2-thio-imidazolidin-1-yl)-3-hydroxy-propanoic acid methyl ester 
• 1228693-57-9 (S)-2-(4-benzylidene-5-oxo-2-thio-imidazolidin-1-yl)propanoic acid methyl ester 
• 1228693-58-0 (R)-2-(4-benzylidene-5-oxo-2-thio-imidazolidin-1-yl)propanoic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and fungicidal activities of derivatives of 2-alkylthio-3-amino- 4H-imidazol-4-one

2-Alkylthio-3-phenylamino-5-arylmethylene-4H-imidazol-4-ones 5 were synthesized by S-alkylation of 3-phenylamino-2-thioxo-4-imidazolidinones 4, which were obtained via cyclization of isothiocyanates 2 with phenylhydrazine in presence of solid potassium ca

Facile synthesis of 2-alkylthio-3-alkyl-5-phenylmethylidene-4H-imidazol-4- ones

2-Alkylthio-3-alkyl-5-phenylmethylidene-4H-imidazol-4-ones 6 were synthesized by N-alkylation and S-alkylation of 2-thioxo-5-phenylmethylidene-4- imidazolidinone 5, which was obtained via cyclization of vinyl isothiocyanate 4 with excess ammonium hydroxid

Synthesis and biological activities of new chiral imidazolinone derivatives

New optically active 2-thio-4-imidazolinones 3 with a chiral carbon at position-3 were synthesized from isothiocyanates 2, which were obtained from aza-Wittig reactions of vinyliminophosphoranes 1 with CS2, with easily accessible chiral (S)- or (R)-amino acid methyl ester hydrochlorides. 2-Methylthio-4H-imidazolin-4-ones 4 were obtained by the S-alkylation of compounds 3 in the presence of K2CO3 causing partial racemization of the enantiomeric pure products. These compounds were identified by MS, IR, 1H NMR, 13C NMR spectroscopy, and elemental analysis. The structures of enantiomers 3c and 3d were also confirmed by X-ray diffraction analysis. The results of preliminary bioassay indicated that compounds 4 exhibited growth inhibition of barnyard grass and cole root and stalk, and fungicidal activities against Fusarium oxysporium, Rhizoctonia solani, Gibberella zeae, Dothiorella gregaria, and Colletotrichum gossypii. Supplemental materials are available for this article. Go to the publisher′s online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

Facile synthesis of 2-alkylthio-5-phenylmethylene-4H-imidazol-4-ones

The facile synthesis of 2-alkylthio-5-phenylmethylene-4H-imidazol-4-ones was discussed. Using reagents like RI and BrCH2COR the alkylation reaction was carried out at room temperature, while it was carried out at 50°C-60°C with other reagents. The stretching mode of C=C showed relatively strong absorption at about 1635 cm-1.