51146-39-5

Upstream product

• 622-42-4 1-nitro-1-phenylmethane 
• 75-77-4 chloro-trimethyl-silane 
• 10416-58-7 N,N-bis(trimethylsilyl)acetamide 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 100-39-0 benzyl bromide 

Downstream Products

• 106808-15-5 3-phenyl-5-<(phenylsulfonyl)methyl>isoxazole 
• 133706-01-1 ((1S,5R,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-(3-phenyl-2-trimethylsilanyloxy-isoxazolidin-5-yl)-methanone 
• 20408-11-1 (E)-N,N-dimethyl-2-nitro-2-phenylethenamine 
• 201024-81-9 C,N-diphenylnitrone 
• 119897-84-6 ((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)((S)-3-phenyl-4,5-dihydroisoxazol-5-yl)methanone 
• 119897-84-6 ((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)((R)-3-phenyl-4,5-dihydroisoxazol-5-yl)methanone 

Relevant academic research and scientific papers

Reactions of silyl nitronates with dimethylformamide dimethyl acetal as a new general procedure for the synthesis of 2-nitroenamines

Silyl nitronates obtained in situ from the corresponding aliphatic nitro compounds react with dimethylformamide dimethyl acetal giving 2-nitroenamines in moderate to good yields. The reaction pathway is discussed.

A novel general method for the synthesis of nitrones by reaction of nitroso compounds with anions of aliphatic nitro compounds

Anions of aliphatic nitro compounds R1R2C=NO2- react with nitroso compounds RNO to give nitrones R1R2C=N(O)R. Salts of nitro compounds with metals and Et3N, as well as trimethylsilyl nitronates in the presence of F-, can serve as the sources of the anions. The structure of the nitrones was established by NMR spectroscopy. 1,3-Dipolar cycloaddition of a series of the nitrones obtained to olefins was investigated.

Asymmetric silyl nitronate cycloadditions with bornane-10,2-sultam derivatives

Asymmetric silyl nitronate cycloadditions with N-acryloyl (2R)-bornane-10,2-sultam, N-acryloyl (2S)-bornane-10,2-sultam, and N-methacryloyl (2R)-bornane-10,2-sultam have been studied. The asymmetric silyl nitronate cycloaddition/elimination methodology pr

Asymmetric induction in silyl nitronate cycloadditions to Oppolzer's chiral sultam derivatives

Silyl nitronate cycloadditions to Oppolzer's chiral sultam derivatives, followed by the elimination of the silyl alcohols from the resulting N-silyloxyisoxazolidines, provide Δ2-isoxazolines in good stereoselectivity (ca. 89/11). The favored transition state is suggested in the light of the X-ray crystal structure of a major cycloadduct.

Reactions of Trialkylsilyl Trifluoromethanesulfonates, IV. - 1,3-Trialkylsiloxy Shift - a New Rearrangement Reaction During the Silylation of Nitroalkanes

Nitroalkanes 1 with C-H bonds in β-position react with two-fold molar amounts of trialkylsilyl triflates 2 in the presence of triethylamine to yield 2-(trialkylsiloxy)oxime O-trialkylsilyl ethers 5 by 1,3-trialkylsiloxy shift.Oxime ethers 5 are also obtai