51176-79-5Relevant academic research and scientific papers
Regioselective alkylation of saccharin with alcohols under Mitsunobu conditions
Wang, Xiaolong,Ma, Yanying,Ju, Tingting
, p. 417 - 419 (2013/09/12)
The regioselective Mitsunobu alkylation of saccharin with various alcohols has been examined. The N/O-alkylation is dependent on the steric hindrance of the alcohols, that is, less sterically hindered alcohol preferentially afford N-alkylated saccharin an
Sulfonamide ligands attained through opening of saccharin derivatives
Robinson, Richard I.,Fryatt, Ross,Wilson, Claire,Woodward, Simon
, p. 4483 - 4489 (2007/10/03)
Literature N-alkylsaccharins (saccharin-R2) have been shown in some cases to be O-alkylated regioisomers by crystallography (3 structures). The genuine former species react with (S)-H2NCHR1CH 2OH at 101°C in dio
Metal-assisted reactions. Part 27. 3-benzyloxy-1,2-benzisothiazole 1,1-dioxide: An unusual ether linkage that does not permit heterogeneous catalytic hydrogenolysis
Brigas, Amadeu F.,Goncalves, Pedro M.,Johnstone, Robert A. W.
, p. 2603 - 2605 (2007/10/03)
Aryl or allyl ethers of some heterocyclic systems can be readily hydrogenolysed or cross-coupled catalytically with transition metals to give arenes, alkenes or alkanes. Unexpectedly for transition metals, the corresponding alkyl and, particularly, benzyl
