51314-26-2Relevant academic research and scientific papers
Studies on organophosphorus compounds 55. A new and facile synthetic route to 1-alkyl(aryl)-2-amino-1-hydroxyalkylphosphonic acids
Yuan,Chen
, p. 531 - 532 (2007/10/02)
Nucleophilic addition of dimethyl phosphite to acylamino ketones prepared conveniently by the Dakin-West reaction involving reaction of the corresponding α-amino acids and acid anhydrides, followed by subsequent hydrolysis affords 1-alkyl(aryl)-2-amino-1-hydroxyalkylphosphonic acids in satisfactory yield.
STUDIES ON ORGANOPHOSPHORUS COMPOUNDS 54. SYNTHESIS OF 1-HYDROXY-1-ALKYL(ARYL)-2-AMINOETHYLPHOSPHONIC ACIDS AND DERIVATIVES THEREOF
Yuan, Chengye,Wang, Guohong,Shoujun, Chen,Maier, Ludwig
, p. 111 - 118 (2007/10/02)
An improved method is developed for the synthesis of 1-hydroxy-1-alkyl(aryl)-2-aminoethylphosphonic acids based on hydrogenation of dialkyl 1-hydroxy-1-alkyl(aryl)-2-nitroethylphosphonates over Raney nickel in acidic medium followed by hydrolysis.The inst
