4190-14-1

Basic information

• Product Name: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE
• Synonyms: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE;N-Phenacylbenzamide;N-(2-keto-2-phenyl-ethyl)benzamide
• CAS NO: 4190-14-1
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.26922
• Mol File: 4190-14-1.mol
• Article Data: 22

Chemical Properties

• Melting Point: 125 °C
• Boiling Point: 478.9 °C at 760 mmHg
• Flash Point: 197.2 °C
• Appearance: /
• Density: 1.163 g/cm³
• Vapor Pressure: 2.48E-09mmHg at 25°C
• Refractive Index: 1.59
• PKA: 13.10±0.46(Predicted)
• CAS DataBase Reference: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE(4190-14-1)
• EPA Substance Registry System: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE(4190-14-1)

Safety Data

• Hazardous Substances Data: 4190-14-1(Hazardous Substances Data)

Usage

General Description

N-(2-oxo-2-phenylethyl)benzamide is a chemical compound with the molecular formula C15H13NO2. It is a benzamide derivative that contains a phenylethyl group linked to a benzene ring. N-(2-OXO-2-PHENYLETHYL)BENZAMIDE is used in various research and laboratory settings as a reagent and intermediate in the synthesis of pharmaceuticals and other organic compounds. It has also been studied for its potential pharmacological properties, including its ability to interact with biological targets and its potential as a drug candidate. The compound's specific applications and properties may vary depending on the context in which it is used.

InChI:InChI=1/C15H13NO2/c17-14(12-7-3-1-4-8-12)11-16-15(18)13-9-5-2-6-10-13/h1-10H,11H2,(H,16,18)

Upstream product

• 53587-10-3 hippuryl chloride 
• 71-43-2 benzene 
• 100-47-0 benzonitrile 
• 7654-06-0 3-phenyl-2H-azirine 
• 93-97-0 benzoic acid anhydride 
• 56-40-6 glycine 
• 77214-41-6 N-<(Trimethylsilyl)methyl>-N-benzoylbenzamide 
• 495-69-2 Hippuric Acid 
• 100-58-3 phenylmagnesium bromide 
• 1816-88-2 2-azido-1-phenylethan-1-one 
• 26086-60-2 2-azido-4'-chloroacetophenone 
• 16717-64-9 1-azidostyrene 
• 65-85-0 benzoic acid 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 41542-84-1 N-(1-hydroxymethyl-2-oxo-2-phenyl-ethyl)-benzamide 
• 412337-98-5 3-benzoylamino-2-phenyl-quinoline-4-carboxylic acid 
• 54167-91-8 N-(2-amino-4-phenyl-thiazol-5-yl)-benzamide 
• 30057-86-4 N-(1-Benzoyl-pentyl)-benzamide 
• 151255-57-1 3-(2-oxo-2-phenyl-ethyl)-benzo[e][1,3]oxazine-2,4-dione 
• 30057-88-6 N-(1-Benzoyl-3-phenyl-propyl)-benzamide 
• 30057-87-5 benzoic acid-(1-benzoyl-3-methyl-butylamide) 
• 111059-46-2 (-)-N-benzoyl-2-hydroxy-2-phenylethylamine 
• 116126-03-5 (S)-N-benzoyl-β-hydroxyphenylethylamine 
• 51314-26-2 1-Hydroxy-1-phenyl-2-aminoethylphosphonsaeure 
• 92-71-7 2,5-diphenyloxazole 
• 3704-40-3 2,5-diphenyl-1,3-thiazole 
• 22020-69-5 oxytriphine 
• 36710-53-9 2-phenyl-quinolin-3-ylamine 

Relevant articles and documents

Muricatisine - A new alkaloid from two species of Oxytropis

The new alkaloid muricatisine has been isolated from the epigeal parts of the plants Oxytropis muricata (Pall.) DC. (Mongolia) and O. puberula Boriss. (Kazakhstan), which belong to the Fabaceae family, and its structure has been established on the basis of spectral characteristics as N-benzoyl-2-oxo-2-phenylethylamine and has been confirmed by a partial synthesis.

Synthesis method of alpha-acylamino ketone compound

The invention discloses a synthesis method of an alpha-acylamino ketone compound, and belongs to the technical field of organic synthesis. The preparation method comprises the following steps: mixingan alkenyl azide compound 1, a carboxylic acid compound 2 and an organic solvent, and heating to react to obtain the alpha-acylamino ketone compound 3. Compared with the prior art, the method has thefollowing advantages: (1) the synthesis process is simple and efficient, no catalyst is needed in the whole process, and the alpha-acylamino ketone compound can be obtained with high yield by dissolving the alkenyl azide compound and the carboxylic acid compound in the solvent and stirring; (2) raw materials are cheap and easy to obtain, reaction conditions are mild, and operation is simple; (3) the substrate is wide in application range and can be used for modifying drug molecules; and (4) the atom economy is high, and the requirements of green chemistry are met.

Remote C(sp3)-H Oxygenation of Protonated Aliphatic Amines with Potassium Persulfate

This letter describes the development of a method for selective remote C(sp3)-H oxygenation of protonated aliphatic amines using aqueous potassium persulfate. Protonation serves to deactivate the proximal C(sp3)-H bonds of the amine substrates and also renders the amines soluble in the aqueous medium. These reactions proceed under relatively mild conditions (within 2 h at 80 °C with amine as limiting reagent) and do not require a transition metal catalyst. This method is applicable to a variety of types of C(sp3)-H bonds, including 3°, 2°, and benzylic C-H sites in primary, secondary, and tertiary amine substrates.