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5132-30-9

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5132-30-9 Usage

Chemical Properties

Off White Solid

Uses

A short, sulfhydryl reactive homobifunctional crosslinking reagent.

General Description

BMOE, BMB and BMH are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. Because BMOE, BMB and BMH have the same reactivity but differ in length, the relative success of these three reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.

Check Digit Verification of cas no

The CAS Registry Mumber 5132-30-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,3 and 2 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5132-30:
(6*5)+(5*1)+(4*3)+(3*2)+(2*3)+(1*0)=59
59 % 10 = 9
So 5132-30-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O4/c13-7-1-2-8(14)11(7)5-6-12-9(15)3-4-10(12)16/h1-4H,5-6H2

5132-30-9 Well-known Company Product Price

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  • TCI America

  • (E0482)  1,2-Bis(maleimido)ethane  >98.0%(N)

  • 5132-30-9

  • 100mg

  • 1,690.00CNY

  • Detail

5132-30-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2-(2,5-dioxopyrrol-1-yl)ethyl]pyrrole-2,5-dione

1.2 Other means of identification

Product number -
Other names Ethylenebiemaleimide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5132-30-9 SDS

5132-30-9Relevant articles and documents

Highly potent and stable capped siRNAs with picomolar activity for RNA interference

Wei, Lv,Cao, Liqiang,Xi, Zhen

, p. 6501 - 6503 (2013)

Put a cap on it: Hairpin-shaped RNAs and dumbbell-shaped RNAs were prepared using a thiol-maleimino Michael addition and exhibited good serum and thermal stability. These capped structures were shown to be cleaved by Dicer and RNA interference (RNAi) experiments showed that RhpRNA (see picture, top right) was highly efficient at RNAi with an IC50 value of 6 pM. Copyright

Preparation method of bismaleimide alkyl compound

-

Paragraph 0060; 0066-0071; 0075-0077, (2020/09/23)

The invention provides a preparation method of a bismaleimide alkyl compound, comprising the following steps of: S1. carrying out ring-opening reaction on cis-butadiene maleic anhydride and a diaminoalkyl compound in a first solvent to obtain an intermediate; and S2, carrying out a ring closing reaction on the intermediate in a second solvent in the presence of an organic alkali to obtain the bismaleimide alkyl compound. According to the preparation method of the bismaleimide alkyl compound disclosed by the embodiment of the invention, the cheap raw materials of maleic anhydride and diaminoalkyl compound are used as the raw materials, and the whole operation avoids long-time high-temperature reaction and reduces the production cost; besides, the trouble of column passing is avoided through later purification, the yield is greatly increased while operation is convenient, and the method is suitable for industrial production and has a good application prospect.

Cp?Co(III)-Catalyzed C-H Alkylation with Maleimides Using Weakly Coordinating Carbonyl Directing Groups

Mandal, Rajib,Emayavaramban, Balakumar,Sundararaju, Basker

supporting information, p. 2835 - 2838 (2018/05/29)

A novel protocol for ortho-C-H alkylation of aromatic and heteroaromatic ketones and esters under Cp?Co(III) catalysis has been developed for the first time. The reaction proceeds through initial cyclometalation via weak chelation-assisted C-H bond activation, followed by coordination of activated alkene, insertion between Co-C, and protodemetalation.

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