51333-90-5

Basic information

• Product Name: 1-(2-CHLORO-ETHYL)-PYRROLIDIN-2-ONE
• Synonyms: AKOS BB-6929;1-(2-CHLORO-ETHYL)-PYRROLIDIN-2-ONE;ASINEX-REAG BAS 07466557;TIMTEC-BB SBB010314;1-(2-chloroethyl)-2-pyrrolidinone
• CAS NO: 51333-90-5
• Molecular Formula: C₆H₁₀ClNO
• Molecular Weight: 147.6
• Mol File: 51333-90-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 118.0-119.5 °C(Press: 7 Torr)
• Appearance: /
• Density: 1.1932 g/cm3
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.63±0.20(Predicted)
• CAS DataBase Reference: 1-(2-CHLORO-ETHYL)-PYRROLIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-CHLORO-ETHYL)-PYRROLIDIN-2-ONE(51333-90-5)
• EPA Substance Registry System: 1-(2-CHLORO-ETHYL)-PYRROLIDIN-2-ONE(51333-90-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 51333-90-5(Hazardous Substances Data)

Usage

General Description

1-(2-chloro-ethyl)-pyrrolidin-2-one, also known as PCP, is a chemical compound that belongs to the class of pyrrolidine derivatives. It is a colorless liquid with a characteristic odor and is primarily used as a precursor in the synthesis of pharmaceuticals and agrochemicals. PCP is also used in the production of plastics, resins, and specialty chemicals. It is important to handle this compound with caution, as it can be harmful if it comes into contact with the skin, eyes, or lungs. Ingestion or inhalation of PCP can cause irritation, nausea, and other health effects, so appropriate safety measures should be taken when working with this chemical.

Upstream product

• 96-48-0 4-butanolide 
• 141-43-5 ethanolamine 
• 616-45-5 2-pyrrolidinon 
• 107-04-0 1-Bromo-2-chloroethane 
• 3445-11-2 1-(2-hydroxyethyl)-2-pyrrolidinone 

Downstream Products

• 54506-42-2 1-{2-[4-(8-chloro-2-methyl-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-piperazin-1-yl]-ethyl}-pyrrolidin-2-one 
• 3001-72-7 DBN 
• 24299-77-2 methyl 3-(2'-oxo-1'-pyrrolidinyl)propanoate 
• 77191-38-9 3-(2-oxopyrrolidin-1-yl)propionic acid 
• 3445-11-2 1-(2-hydroxyethyl)-2-pyrrolidinone 
• 117018-92-5 N--2-pyrrolidone hydrochloride 
• 104087-51-6 1-(2-{4-[(1R,3S)-6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-pyrrolidin-2-one 
• 7435-92-9 trimethyl-[2-(2-oxo-pyrrolidino)-ethyl]-ammonium; iodide 
• 13839-15-1 1-(2-mercapto-ethyl)-pyrrolidin-2-one 
• 88-12-0 1-ethenyl-2-pyrrolidinone 
• 930298-36-5 1-(2-{2,4-dichloro-5-[2-chloro-9-(4-methoxy-benzyl)-9H-purin-6-yl]-phenoxy}-ethyl)-pyrrolidin-2-one 

Relevant articles and documents

N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The present invention provides the compounds having the general formula: (I) wherein R1 to R8, and X are as described herein, compositions including the compounds and methods of using the compounds.

HYDANTOIN AND THIOHYDANTOIN DERIVATIVES AS ANTIVIRAL DRUGS

The present invention relates to a compound of the following formula (I), or a salt, solvate, tautomer, enantiomer, diastereoisomer or racemic mixture thereof: as well as its use as a drug, notably in the treatment of hepatitis C, its preparation process, and the pharmaceutical compositions containing such a compound.

HYDROFORMYLATION PROCESS FOR THE CONVERSION OF AN ETHYLENICALLY UNSATURATED COMPOUND TO AN ALCOHOL

The invention pertains to a hydroformylation process for the conversion of an ethylenically unsaturated compound to an alcohol comprising a first step of reacting at an elevated temperature in a reactor the ethylenically unsaturated compound, carbon monox