514797-98-9 Usage
Uses
Used in Pharmaceutical Synthesis:
5-Chloro-3-fluoro-2-iodopyridine is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Production:
5-chloro-3-fluoro-2-iodopyridine also serves as an intermediate in the production of agrochemicals, playing a crucial role in the creation of pesticides and other agricultural products designed to protect crops and enhance yields.
Used in Organic Synthesis:
As a building block in organic synthesis, 5-chloro-3-fluoro-2-iodopyridine is valuable for constructing complex organic molecules. Its presence in these syntheses can lead to the development of novel compounds with potential applications across various industries.
Used in Medicinal Chemistry and Drug Discovery:
Due to its distinctive structural features and reactivity, 5-chloro-3-fluoro-2-iodopyridine holds promise in the field of medicinal chemistry. It is employed in drug discovery processes, where it may contribute to the design and synthesis of innovative therapeutic agents.
Used in Research and Development:
5-chloro-3-fluoro-2-iodopyridine is the subject of ongoing research for a variety of industrial and scientific applications. Its unique attributes make it an important candidate for exploration in both academic and commercial research settings, potentially leading to new breakthroughs in multiple fields.
Check Digit Verification of cas no
The CAS Registry Mumber 514797-98-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,4,7,9 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 514797-98:
(8*5)+(7*1)+(6*4)+(5*7)+(4*9)+(3*7)+(2*9)+(1*8)=189
189 % 10 = 9
So 514797-98-9 is a valid CAS Registry Number.
514797-98-9Relevant academic research and scientific papers
Creating structural manifolds from a common precursor: Basicity gradient-driven isomerization of halopyridines
Schlosser, Manfred,Bobbio, Carla
, p. 4174 - 4180 (2007/10/03)
5-Chloro-2,3-difluoropyridine, an intermediate in the manufacturing process of an industrial pesticide, can be hydrolyzed to 5-chloro-3-fluoro-2H-pyridinone and the latter converted into 2,5-dichloro-3-fluoropyridine (1a), 2-bromo-5-chloro-3-fluoropyridine (1b), 5-chloro-3-fluoro-2-iodopyridine (1c) and 3-chloro-5-fluoropyridine (1d). Consecutive treatment of these four substrates with lithium diisopropylamide and carbon dioxide or lithium diisopropylamide and iodine affords the corresponding 4-pyridinecarboxylic acids 2 and 4-iodopyridines 3, respectively. Amide-promoted deprotonation of such 4-iodopyridines 3 triggers an isomerization in which lithium and iodine change places. The resulting species can be trapped with carbon dioxide to give the acids 5a-c or neutralized to give the halopyridines 4a-c. The iodopyridines 4a and 4b can be converted into the acids 6a and 6b, the latter product leading also to the congeners 6c and 6d. The diiodopyridine 4c provides an entry to the halopyridine 4d, which at the same time may act as the precursor to the acid 5d, the acid 7 or the bisacid 8. Finally, the acid 9 is accessible from either one of the 5-chloro-3-fluoro-2-halopyridines 1b and 1c. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2002).
