51483-21-7

Basic information

• Product Name: 6-chloro-4-phenylquinazoline-2-carbonitrile
• Synonyms: 6-chloro-4-phenylquinazoline-2-carbonitrile
• CAS NO: 51483-21-7
• Molecular Weight: 265.702
• Mol File: 51483-21-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-chloro-4-phenylquinazoline-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-4-phenylquinazoline-2-carbonitrile(51483-21-7)
• EPA Substance Registry System: 6-chloro-4-phenylquinazoline-2-carbonitrile(51483-21-7)

Safety Data

• Hazardous Substances Data: 51483-21-7(Hazardous Substances Data)

Upstream product

• 4797-43-7 6-chloro-4-phenylquinazolin-2-ol 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 773837-37-9 sodium cyanide 
• 5185-54-6 2-chloro-4-phenyl-6-chloroquinazoline 

Downstream Products

• 5958-08-7 6-chloro-4-phenylquinazoline-2-carboxylic acid 

Relevant articles and documents

4-ARYLQUINAZOLINE DERIVATIVES AS INHIBITORS OF METHIONINE ADENOSYLTRANSFERASE 2A

The invention relates to certain derivatives of 4-arylquinazoline formula (I) which are inhibitors of methionine adenosyltransferase 2A (MAT2A). The invention also relates to pharmaceutical compositions comprising such compounds and methods of treating diseases that can be treated by inhibition of MAT2A such as cancer, including cancers characterized by reduced or no activity of methylthioadenosine phosphorylase (MTAP).

Heterocycles. IV. Reactions of 2 amino 3H 1,4 benzodiazepines with primary amines and hydroxylamines

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