51535-47-8

Basic information

• Product Name: α-cyclohexyl-p-tolylacetic acid
• Synonyms: α-cyclohexyl-p-tolylacetic acid
• CAS NO: 51535-47-8
• Molecular Weight: 232.323
• Mol File: 51535-47-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α-cyclohexyl-p-tolylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: α-cyclohexyl-p-tolylacetic acid(51535-47-8)
• EPA Substance Registry System: α-cyclohexyl-p-tolylacetic acid(51535-47-8)

Safety Data

• Hazardous Substances Data: 51535-47-8(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 28047-24-7 (Chlor)cyclohexyl(p-tolyl)methan 
• 104-87-0 4-methyl-benzaldehyde 
• 28047-28-1 cyclohexyl-(p-methylphenyl)-methanol 
• 108-85-0 1-bromocyclohexane 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 622-47-9 4-tolylacetic acid 
• 953-91-3 cyclohexyl tosylate 
• 81311-83-3 2-cyclohexyl-2-(4-methylphenyl)acetonitrile 

Downstream Products

• 76618-86-5 2-Cyclohexyl-2-(p-tolyl)ethyl-p-toluolsulfonat 
• 81311-85-5 N,2-dicyclohexyl-2-p-tolylethylamine 
• 81311-84-4 2,N-Dicyclohexyl-2-p-tolyl-acetamide 
• 81519-02-0 Cyclohexyl-p-tolyl-acetyl chloride 

Relevant articles and documents

Discovery of new C3aR ligands. Part 2: Amino-piperidine derivatives

The synthesis and structure-activity relationships against the C3a receptor of a series of substituted aminopiperidine derivatives are reported. DMPK properties and functional activities of selected compounds are described. The compounds obtained are the first non-arginine ligands of C3aR.

Solvolysis of 2-Cyclohexyl-2-phenylethyl Tosylates Substituted at the Phenyl Ring

The solvolysis of 2-cyclohexyl-2-phenylethyl tosylates substituted at the phenyl ring by X= p-H (1), p-NO2, p-IO2, p-CN, p-COCH3, m-Cl, m-F, p-Cl, p-Br, p-CH3, and p-OCH3 (2a-k) in ethanol, acetic acid, and formic acid has been investigated.The total rate constants kt were determined and the obtained values together with corresponding Hammett ? constants were used to calculate the rate constants kΔ (for aryl-assisted reactions) and ks (for non-assisted reactions).The acetolysis values FkΔ and ks of 2-cyclohexyl-2-phenylethyl tosylate (1) at 100 deg C are in good agreement with those formerly obtained on the basis of product analysis.