51575-84-9

Usage

Type of Compound

Chlorinated alkyne

Structure

Contains a triple bond between two carbon atoms and a chlorine atom attached to one of the carbons

Usage

Organic synthesis

Application

Forming carbon-carbon bonds and creating complex molecules

Role

Precursor in the production of pharmaceuticals and agrochemicals

Utilization

Research and development labs for various chemical reactions and processes

Safety Precaution

Handle with caution due to toxicity and reactivity

Upstream product

• 58534-80-8 NaCC(n-C₃H₇) 
• 109-70-6 1.3-chlorobromopropane 
• 2677-33-0 1,1,5-trichloro-pent-1-ene 
• 676-58-4 methylmagnesium chloride 
• 2234-82-4 1-propylmagnesium chloride 
• 3993-94-0 1,1,7-trichloro-1-heptene 
• 627-19-0 1-Pentyne 

Downstream Products

• 24612-83-7 Oct-1-en-4-yne 
• 56630-34-3 non-5-ynoic acid 

Relevant academic research and scientific papers

CROSS COUPLING OF 1,1,ω-TRICHLORO-1-ALKENES WITH ALKYLMAGNESIUM CHLORIDES WITH CATALYSIS BY PALLADIUM(II) AND COPPER(II) COMPLEXES AND SYNTHESIS OF 10-PROPYL-5(E),9-TRIDECADIEN-1-YL ACETATE ("PROPYLURE")

The cross coupling of 1,1,ω-trichloro-1-alkenes with RMgCl (R=CH3, C3H7, C4H9) was realized with (Ph3P)2PdCl2 and Li2CuCl4 as catalysts.The two vinylic chlorine atoms are substituted by the alkyl groups without affecting the chlorine atom in the chloromet

Kolbe Synthesis of Unsaturated Pheromones by Coelectrolysis with 5-Alkynoic Acids

The alkynoic acids 5a - g are synthesized by coelectrolysis of 5-alkynoic acids 2a - c with dicarboxylic monoesters 3a - d.By reduction, Lindlar-hydrogenation, and acetylation these are converted into pheromones such as (Z)-11-hexadecenyl acetate (7b), the pheromone of Mamestra brassicae. 2a - c can be prepared by alkynylation of 1-bromo-3-chloropropane to 1a - c, substitution by cyanide and hydrolysis.