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(22E)-5α-Ergosta-8,14,22-trien-3β-ol, commonly known as ergosterol, is a significant sterol compound predominantly found in fungi, particularly within the cell membranes of yeast and other fungi. It is instrumental in maintaining the structural integrity and fluidity of these organisms' cell membranes. Ergosterol also acts as a precursor for the synthesis of vitamin D2 when subjected to ultraviolet light, and it has been investigated for its potential therapeutic applications, such as anti-inflammatory, antioxidant, and anticancer properties. This vital compound is integral to fungal biology and has attracted attention for its potential health benefits.

516-88-1

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516-88-1 Usage

Uses

Used in Pharmaceutical Industry:
(22E)-5α-Ergosta-8,14,22-trien-3β-ol is utilized as a precursor for the synthesis of vitamin D2, which is essential for maintaining bone health and immune function. Its conversion to vitamin D2 upon exposure to ultraviolet light makes it a valuable component in the development of vitamin D supplements and fortified products.
Used in Anticancer Applications:
Ergosterol is employed as a potential anticancer agent due to its ability to modulate various cellular processes and pathways associated with cancer development and progression. Its potential therapeutic applications are currently under investigation, with the aim of developing novel cancer treatments that leverage its bioactive properties.
Used in Antioxidant and Anti-Inflammatory Applications:
(22E)-5α-Ergosta-8,14,22-trien-3β-ol is used as a natural antioxidant and anti-inflammatory agent, given its capacity to combat oxidative stress and reduce inflammation. These properties make it a promising candidate for the development of health supplements and pharmaceuticals targeting inflammatory and oxidative stress-related conditions.
Used in Fungal Biology Research:
Ergosterol is used as a marker for fungal presence and activity in various research applications. Its unique role in fungal cell membranes allows scientists to study fungal growth, pathogenicity, and response to antifungal agents, contributing to the advancement of fungal biology and the development of new antifungal therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 516-88-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 516-88:
(5*5)+(4*1)+(3*6)+(2*8)+(1*8)=71
71 % 10 = 1
So 516-88-1 is a valid CAS Registry Number.

516-88-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name Ergosta-8(9),14(15),22(23)-trien-3β-ol

1.2 Other means of identification

Product number -
Other names 5α-ergosta-8,14,22-trien-3β-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:516-88-1 SDS

516-88-1Relevant academic research and scientific papers

REGIOCONTROLLED SYNTHESIS OF THE ERGOSTEROL B-ISOMERS

Dolle, Roland E.,Schmidt, Stanley J.,Kruse, Lawrence I.

, p. 1581 - 1582 (2007/10/02)

A novel, regiocontrolled synthesis of the ergosterol B-isomers, (1), (2) and (3) is described, the success of which was realized via the highly regioselective formation of intermediate trienoltriflates, (7), (8) and (9).

Structure and Chemistry of ?-Allyl Palladium Complexes from Steroids

Mahe, Christian,Patin, Henri,Hulle, Marie-Therese Van,Barton, Derek H.R.

, p. 2504 - 2508 (2007/10/02)

The synthesis and structures of ?-allyl palladium complexes prepared from vitamins D2 and D3 and from ergosterol, 7,8-didehydrocholesterol, and 3-epi-cholesterol are described.The mechanism of palladisation is descussed as well as the transformation of the complexes into conjugated trienes or allylic alcohols.

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