51626-58-5

Basic information

• Product Name: (1H-indol-3-yl)(phenyl)methanol
• Synonyms: (1H-indol-3-yl)(phenyl)methanol
• CAS NO: 51626-58-5
• Molecular Weight: 223.274
• Mol File: 51626-58-5.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: (1H-indol-3-yl)(phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1H-indol-3-yl)(phenyl)methanol(51626-58-5)
• EPA Substance Registry System: (1H-indol-3-yl)(phenyl)methanol(51626-58-5)

Safety Data

• Hazardous Substances Data: 51626-58-5(Hazardous Substances Data)

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 1589-82-8 phenylmagnesium bromide 
• 100-58-3 phenylmagnesium bromide 
• 153942-69-9 3-bromo-1-(tert-butyl-dimethyl-silanyl)-1H-indole 
• 40899-73-8 N-tert-butyldimethylsilylindole 
• 120-72-9 indole 
• 603-76-9 1-methylindole 
• 100-52-7 benzaldehyde 
• 2175-90-8 6,6-Diphenylfulvene 
• 64-17-5 ethanol 
• 135-19-3 β-naphthol 
• 1554539-46-6 C₁₈H₂₁NOSi 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 35173-74-1 3,3'-bis-indolyl(phenyl)methane 
• 16886-10-5 3-benzyl-1H-indole 
• 1239950-41-4 3-(hydroxyphenylmethyl)indole-1-carboxylic acid tert-butyl ester 
• 1392144-90-9 tert-butyl 3-benzoyl-1H-indole-1-carboxylate 

Relevant articles and documents

Accelerating Amine-Catalyzed Asymmetric Reactions by Intermolecular Cooperative Thiourea/Oxime Hydrogen-Bond Catalysis

The ability of intermolecular cooperative thiourea/oxime hydrogen-bond catalysis for improving and accelerating asymmetric aminocatalysis is presented. The two readily available hydrogen-bond-donating catalysts operates in synergy with a chiral amine catalyst to accomplish highly stereoselective transformations. The synergistic catalyst systems simultaneously activate both electrophiles and nucleophiles, and make the transformations more chemo- and stereoselective. This was exemplified by performing co-catalytic enantioselective direct intermolecular α-alkylation reactions of aldehydes, direct aldol reactions, and asymmetric conjugate reactions, which gave the corresponding products in high yields and enantiomeric ratios.

Base-Promoted Three-Component One-Pot Approach to 3-(α,α-Diarylmethyl)indoles via Arylation of 3-Indolylalcohols

A base-promoted 3-component one-pot approach to 3-(α,α-diarylmethyl)indoles via arylation of in situ generated 3-indolylalcohols in ethanol-water solvent system is reported. Use of acid catalysts or neutral organocatalysts does not offer the desired product, but furnish bis(indolyl)methanes instead. Electron-rich aromatics such as naphthols and phenols are preferably employed for arylation. The atom economy, use of green solvent, and the multicomponent strategy are the notable features of the reaction.

Lewis Acid-Catalyzed [3+3] Annulation of Donor-Acceptor Cyclopropanes and Indonyl Alcohols: One Step Synthesis of Substituted Carbazoles with Promising Photophysical Properties

A highly efficient protocol to access carbazole from donor-acceptor cyclopropane and indonyl alcohol via [3+3] annulation in the presence of a Lewis acid has been demonstrated. This method facilitates the post functionalization of the substituted carbazol

One-pot sequential multi-component reaction: Synthesis of 3-substituted indoles

Here, we have developed a 3-component one-pot sequential approach to 3-substituted indoles. The main advantages of this process are step economy, reduced waste, and operational simplicity. The method involves in situ generation of 3-indolylalcohols from t