516447-52-2

Usage

Uses

Used in Pharmaceutical Industry:
1-[1-(4-FLUORO-PHENYL)-ETHYL]-PIPERAZINE is used as a pharmaceutical agent for its potential therapeutic applications in treating various medical conditions. Its unique chemical structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
Used in Medicinal Chemistry Research:
1-[1-(4-FLUORO-PHENYL)-ETHYL]-PIPERAZINE serves as a valuable compound in medicinal chemistry research, where it can be further modified and optimized to enhance its pharmacological properties. 1-[1-(4-FLUORO-PHENYL)-ETHYL]-PIPERAZINE can be used as a starting point for the design and synthesis of new drug molecules with improved efficacy and safety profiles.
Used in Drug Discovery:
1-[1-(4-FLUORO-PHENYL)-ETHYL]-PIPERAZINE is utilized in drug discovery processes to identify novel therapeutic agents with potential applications in various disease areas. Its unique chemical features make it a valuable tool for screening and evaluating its interactions with biological targets, leading to the development of new drugs with innovative mechanisms of action.

Upstream product

• 403-41-8 1-(4-Fluorophenyl)ethanol 
• 462-06-6 fluorobenzene 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 862270-46-0 4-[(1S,1R)-1-(4-fluorophenyl)ethyl]piperazine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 862270-56-2 4-fluoro-6-(4-(1-(4-fluorophenyl)ethyl)piperazin-1-yl)pyrimidine 
• 862461-82-3 7-(6-(4-(1-(4-Fluorophenyl)ethyl)piperazin-1-yl)pyrimidin-4-ylamino)-3,4-dihydroquinolin-2(1H)-one 
• 862461-86-7 5-(6-(4-(1-(4-Fluorophenyl)ethyl)piperazin-1-yl)pyrimidin-4-ylamino)indolin-2-one 
• 862461-87-8 N-(6-(4-(1-(4-Fluorophenyl)ethyl)piperazin-1-yl)pyrimidin-4-yl)benzo[d]thiazol-6-amine 

Relevant academic research and scientific papers

Substituted Cyclic Carboxamide and Urea Derivatives as Ligands of the Vanilloid Receptor

Substituted cyclic carboxamide and urea compounds, a process for their preparation, pharmaceutical compositions containing these compounds, and the use of these compounds for the treatment and/or inhibition of pain and other conditions mediated by the vanilloid receptor 1.

PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION

The invention relates to new piperazine-pieridine compounds having anti-viral activity and particularly anti-HCV activity. The invention further relates to pharmaceutical compositions comprising compounds according to the invention.

Vanilloid receptor ligands and their use in treatments

Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS

Pyrimidine ethers and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

Vanilloid receptor ligands and their use in treatments

Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache,