5165-47-9

Upstream product

• 141-97-9 ethyl acetoacetate 
• 106-47-8 4-chloro-aniline 
• 106-51-4 p-benzoquinone 
• 56963-63-4 ethyl 3-(4-chlorophenylamino)crotonate 

Downstream Products

• 161768-88-3 1-(4-Chloro-phenyl)-5-ethoxycarbonylmethoxy-2-methyl-1H-indole-3-carboxylic acid ethyl ester 
• 173538-49-3 1-(4-Chloro-phenyl)-5-hydrazinocarbonylmethoxy-2-methyl-1H-indole-3-carboxylic acid ethyl ester 
• 161768-95-2 5-Carboxymethoxy-1-(4-chloro-phenyl)-2-methyl-1H-indole-3-carboxylic acid 
• 159187-00-5 1-(4-chloro-phenyl)-4-dimethylaminomethyl-5-hydroxy-2-methyl-indole-3-carboxylic acid ethyl ester 
• 134826-52-1 1-(4-Chloro-phenyl)-5-(3-cyano-4-phenylamino-pyridin-2-yloxy)-2-methyl-1H-indole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Montmorillonite clay catalyzed three component, one-pot synthesis of 5-Hydroxyindole derivatives

A highly efficient and environmentally benign protocol has been developed for the first time to produce a wide range of biologically active 5-hydroxyindole derivatives using montmorillonite KSF clay as a reusable solid acid catalyst. The use of recyclable clay makes this procedure quite simple, more convenient and cost-effective.

Synthesis and biological screening of some new novel indole derivatives

Synthesis of some novel indole derivatives has been undertaken by the reaction of 1,4-benzoquinone with ethyl-β-(arylamino)-crotonates in the presence/absence of nitrogen atmosphere. The products 1a-o have been screened for their antimicrobial activity an