56963-63-4

Upstream product

• 141-97-9 ethyl acetoacetate 
• 106-47-8 4-chloro-aniline 
• 7553-56-2 iodine 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 

Downstream Products

• 890085-53-7 ethyl 3-(4-chlorophenyl)-3,3a,6,12-tetrahydro-3a,7-dihydroxy-2-methyl-6,12-dioxo-naphtho[2,3-d]indole-1-carboxylate 
• 5165-47-9 ethyl 1-(4-chlorophenyl)-5-hydroxy-2-methyl-1H-indole-3-carboxylate 
• 15644-86-7 6-chloro-2-methyl-quinolin-4-ol 

Relevant academic research and scientific papers

Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction

The study of the Vilsmeier-Haack reagent on 4-hydroxyquinaldines resulted in a new versatile intermediate 4-chloro-3-formyl-2-(2-hydroxy-ethene-1-yl)quinolines, which on further treatment with hydrazine hydrate yielded the desired diazepino quinoline derivatives. All the synthesized diazepino quinoline derivatives are screened for their antibacterial and antifungal activities. Cytogenetic analysis of the samples is also reported.

Synthesis and biological screening of some new novel indole derivatives

Synthesis of some novel indole derivatives has been undertaken by the reaction of 1,4-benzoquinone with ethyl-β-(arylamino)-crotonates in the presence/absence of nitrogen atmosphere. The products 1a-o have been screened for their antimicrobial activity an

Vilsmeier-Haack reaction on quinaldines

The study of the Vilsmeier-Haack reaction on 4-hydroxyquinaldines resulted with the preparation of rarely existing 4-chloro-3-formyl-2(vinyl-1-ol)-quinolines.