51676-15-4Relevant academic research and scientific papers
Ru-catalyzed highly enantioselective hydrogenation of α-keto Weinreb amides
Zhao, Meng Meng,Li, Wan Fang,Ma, Xin,Fan, Wei Zheng,Tao, Xiao Ming,Li, Xiao Ming,Xie, Xiao Min,Zhang, Zhao Guo
, p. 342 - 348 (2013/07/26)
Asymmetric hydrogenation of α-keto Weinreb amides has been realized with [Ru((S)-Sunphos)(benzene)Cl]Cl as the catalyst and CeCl3· 7H2O as the additive. A series of enantiopure α-hydroxy Weinreb amides (up to 97% ee) have been obtained. Catalytic amount of CeCl 3·7H2O is essential for the high reactivity and enantioselectivity and the ratio of CeCl3·7H2O to [Ru((S)-Sunphos)(benzene)Cl]Cl plays an important role in the hydrogenation reaction.
Recovery of hydroxy acids from trash
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, (2008/06/13)
This invention is a method for recovering hydroxy acid values from a poly(hydroxy acid) containing source, said method comprising, in order: (a) contacting the source with a solubilizing fluid in an amount of at least 1 mole of solubilizing fluid per mole of hydroxy acid equivalent present in the source, said solubilizing fluid selected from the group consisting of (1) water, (2) alcohols containing 1 to 6 carbon atoms, (3) mixtures of water and said alcohols, (4) amines of the formula HNR1R2, wherein R1 and R2 are independently selected from the group consisting of hydrogen and alkyl groups of 1-4 carbon atoms; (5) liquid media containing diamines of the formula H(R3)NR5N(R4)H, wherein R3 and R4 are independently selected from the group consisting of hydrogen and alkyl groups of 1-4 carbon atoms or are joined to form a heterocyclic ring, and R5 is alkylene of 2-12 carbon atoms or phenylene; and (6) mixtures of said amines and/or diamines with water and/or alcohols containing 1 to 6 carbon atoms.
Preparation of amide derivatives of hydroxy acids
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, (2008/06/13)
Depolymerizing high molecular weight polyhydroxy acid by reacting with an amine to produce an amide derivative.
