51719-46-1

Usage

Structure

Benzene ring with a nitro group (NO2) at the 5-position, chlorine (Cl) atoms at the 1and 2-positions, and a methyl (CH3) group at the 3-position.

Derivative

Nitrobenzene

Usage

Intermediate in the synthesis of various organic compounds, including pharmaceuticals and dyes.

Environmental impact

Potential environmental contaminant.

Health hazard

Toxic and irritant properties, considered hazardous to human health.

Safety precautions

Proper safety measures should be taken when handling this chemical.

Upstream product

• 32768-54-0 2,3-dichlorotoluene 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 69951-02-6 2-chloro-6-methyl-4-nitro-phenylamine 

Downstream Products

• 51719-45-0 3,4-dichloro-5-methylphenylamine 
• 58291-82-0 1-Chloro-2-(4-chloro-phenoxy)-3-methyl-5-nitro-benzene 
• 78983-80-9 3-chloro-4-<(p-chlorophenyl)thio>-5-methylnitrobenzene 
• 53266-59-4 {2-[3-chloro-4-(4-chloro-phenylsulfanyl)-5-methyl-phenyl]-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carbonyl}-carbamic acid ethyl ester 
• 58291-56-8 1-[3-Chloro-4-(4-chloro-phenoxy)-5-methyl-phenyl]-3-((E)-3-ethoxy-acryloyl)-urea 
• 56812-73-8 3-Chloro-4-(4-chloro-phenoxy)-5-methyl-phenylamine 

Relevant academic research and scientific papers

Aminophenyl derivatives as selective androgen receptor modulators

Disclosed herein is a novel class of aminophenyl compounds having the structure: wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or preventi

Transition metal catalysed cross-coupling between benzylic halides and aryl nucleophiles. Synthesis of some toxicologically interesting tetrachlorobenzyltoluenes

The aryl-benzyl cross-coupling in the presence of copper-, nickel- and palladium-catalysts has been investigated with a number of chlorine- and methyl-substituted arylmetal compounds ArM (M = MgBr, ZnCl) and (substituted) benzylic halides ArCH2X. The results have been applied in the selective synthesis of some toxicologically interesting tetrachlorobenzyltoluenes.

Anticoccidial Derivatives of 6-Azauracil. 4. A 1000-fold Enhancement of Potency by Phenyl Sulfide and Phenyl Sulfone Side Chains

We report further progress in exploiting our earlier discovery that the anticoccidial activity of 6-azauracil increases markedly when appropriately substituted benzyl or phenyl groups are attached at N-1.With guidance from previous structure-activity rela