69951-02-6

Basic information

• Product Name: 2-CHLORO-6-METHYL-4-NITROANILINE
• Synonyms: 6-CHLORO-2-METHYL-4-NITROANILINE;6-CHLORO-4-NITRO-P-TOLUIDINE;2-CHLORO-6-METHYL-4-NITROANILINE;TIMTEC-BB SBB003700;6-Chloro-2-methyl-4-nitroaniline,97%;2-Amino-3-chloro-5-nitrotoluene, 4-Amino-3-chloro-5-methylnitrobenzene
• CAS NO: 69951-02-6
• Molecular Formula: C₇H₇ClN₂O₂
• Molecular Weight: 186.6
• EINECS: 237-589-0
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 69951-02-6.mol

Chemical Properties

• Melting Point: 170-175 °C
• Boiling Point: 344.6 °C at 760 mmHg
• Flash Point: 162.2 °C
• Appearance: yellow to dark yellow crystalline powder or needles
• Density: 1.4800 (rough estimate)
• Refractive Index: 1.5560 (estimate)
• Storage Temp.: 2-8°C(protect from light)
• PKA: -1.21±0.20(Predicted)
• CAS DataBase Reference: 2-CHLORO-6-METHYL-4-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-METHYL-4-NITROANILINE(69951-02-6)
• EPA Substance Registry System: 2-CHLORO-6-METHYL-4-NITROANILINE(69951-02-6)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38
• Safety Statements: 37/39-26
• HazardClass: IRRITANT
• Hazardous Substances Data: 69951-02-6(Hazardous Substances Data)

Usage

Chemical Properties

yellow to dark yellow crystalline powder or

Upstream product

• 99-52-5 2-methyl-4-nitro-benzenamine 
• 7553-56-2 iodine 

Downstream Products

• 16582-38-0 3-chloro-5-nitrotoluene 
• 51719-46-1 1,2-dichloro-3-methyl-5-nitrobenzene 
• 77019-79-5 2-chloro-6-methyl-p-phenylenediamine 
• 105788-93-0 N-butyl-glycine-(4-amino-2-chloro-6-methyl-anilide) 
• 74209-22-6 7-chloro-5-nitro-1H-indazole 
• 89642-17-1 2-bromo-1-chloro-3-methyl-5-nitrobenzene 
• 89894-12-2 2-chloro-6-methyl-4-nitrobenzoic acid 
• 22521-39-7 2-chloro-6-methyl-4-nitrobenzoic acid amide 
• 22459-80-9 2-chloro-6-methyl-4-nitrobenzonitrile 
• 1217093-53-2 3-bromo-N-(2-chloro-6-methyl-4-nitrophenyl)-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 
• 102468-87-1 N,N'-(2-chloro-6-methyl-p-phenylene)-bis-benzamide 
• 53266-59-4 {2-[3-chloro-4-(4-chloro-phenylsulfanyl)-5-methyl-phenyl]-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carbonyl}-carbamic acid ethyl ester 
• 38560-81-5 2-<3-chloro-4-<(p-chlorophenyl)thio>-5-methylphenyl>-as-triazine-3,5(2H,4H)-dione 
• 53266-64-1 (2-{[3-Chloro-4-(4-chloro-phenylsulfanyl)-5-methyl-phenyl]-hydrazono}-3-ethoxycarbonylamino-3-oxo-propionyl)-carbamic acid ethyl ester 

Relevant articles and documents

Development of 2, 4-diaminoquinazoline derivatives as potent PAK4 inhibitors by the core refinement strategy

Upon analysis of the reported crystal structure of PAK4 inhibitor KY04031 (PAK4 IC50?=?0.790?μM) in the active site of PAK4, we investigated the possibility of changing the triazine core of KY04031 to a quinazoline. Using KY04031 as a starting

SUBSTITUTED ANILINE DERIVATIVES

The present invention relates to aniline derivatives of the general formula (I) or salts thereof and their use, related to their KCNQ potassium ion channel opening activity.

SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES

The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.

Process for preparing 3-chloro-5-nitrotoluene

A preparation process of 3-chloro-5-nitrotoluene is provided in mild conditions. It is a process for preparing 3-chloro-5-nitrotoluene, which comprises reacting 2-methyl-4-nitroaniline with a chlorinating agent such as 5-butyl hypochlorite in a neutral co

Transition metal catalysed cross-coupling between benzylic halides and aryl nucleophiles. Synthesis of some toxicologically interesting tetrachlorobenzyltoluenes

The aryl-benzyl cross-coupling in the presence of copper-, nickel- and palladium-catalysts has been investigated with a number of chlorine- and methyl-substituted arylmetal compounds ArM (M = MgBr, ZnCl) and (substituted) benzylic halides ArCH2X. The results have been applied in the selective synthesis of some toxicologically interesting tetrachlorobenzyltoluenes.

Anticoccidial Derivatives of 6-Azauracil. 4. A 1000-fold Enhancement of Potency by Phenyl Sulfide and Phenyl Sulfone Side Chains

We report further progress in exploiting our earlier discovery that the anticoccidial activity of 6-azauracil increases markedly when appropriately substituted benzyl or phenyl groups are attached at N-1.With guidance from previous structure-activity rela

P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents

There are provided substituted p-phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters, a method for the preparation of said esters and unsubstituted derivatives thereof and a method for controlling helminths in warm-blooded animals by administering to said animals an anthelmintically effective amount of said unsubstituted or substituted p-phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid ester.

Method for the control of cattle grubs employing a phenylene bis[imino(thio]carbonyl)diphosphor(thio)-amidic acid ester

There is provided a method for controlling the larvae of heel flies which parasitize ruminants and other warm-blooded animals by administering to said animals an effective amount of an unsubstituted or substituted phenylene bis[imino(thio)carbonyl]diphosp