69951-02-6

Basic information

• Product Name: 2-CHLORO-6-METHYL-4-NITROANILINE
• Synonyms: 6-CHLORO-2-METHYL-4-NITROANILINE;6-CHLORO-4-NITRO-P-TOLUIDINE;2-CHLORO-6-METHYL-4-NITROANILINE;TIMTEC-BB SBB003700;6-Chloro-2-methyl-4-nitroaniline,97%;2-Amino-3-chloro-5-nitrotoluene, 4-Amino-3-chloro-5-methylnitrobenzene
• CAS NO: 69951-02-6
• Molecular Formula: C₇H₇ClN₂O₂
• Molecular Weight: 186.6
• EINECS: 237-589-0
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 69951-02-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 170-175 °C
• Boiling Point: 344.6 °C at 760 mmHg
• Flash Point: 162.2 °C
• Appearance: yellow to dark yellow crystalline powder or needles
• Density: 1.4800 (rough estimate)
• Refractive Index: 1.5560 (estimate)
• Storage Temp.: 2-8°C(protect from light)
• PKA: -1.21±0.20(Predicted)
• CAS DataBase Reference: 2-CHLORO-6-METHYL-4-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-METHYL-4-NITROANILINE(69951-02-6)
• EPA Substance Registry System: 2-CHLORO-6-METHYL-4-NITROANILINE(69951-02-6)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38
• Safety Statements: 37/39-26
• HazardClass: IRRITANT
• Hazardous Substances Data: 69951-02-6(Hazardous Substances Data)

Usage

Chemical Properties

yellow to dark yellow crystalline powder or

Upstream product

• 7553-56-2 iodine 
• 99-52-5 2-methyl-4-nitro-benzenamine 

Downstream Products

• 1217093-53-2 3-bromo-N-(2-chloro-6-methyl-4-nitrophenyl)-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 
• 89642-17-1 2-bromo-1-chloro-3-methyl-5-nitrobenzene 
• 89894-12-2 2-chloro-6-methyl-4-nitrobenzoic acid 
• 22521-39-7 2-chloro-6-methyl-4-nitrobenzoic acid amide 
• 22459-80-9 2-chloro-6-methyl-4-nitrobenzonitrile 
• 74209-22-6 7-chloro-5-nitro-1H-indazole 
• 102468-87-1 N,N'-(2-chloro-6-methyl-p-phenylene)-bis-benzamide 
• 105788-93-0 N-butyl-glycine-(4-amino-2-chloro-6-methyl-anilide) 
• 53266-59-4 {2-[3-chloro-4-(4-chloro-phenylsulfanyl)-5-methyl-phenyl]-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carbonyl}-carbamic acid ethyl ester 
• 38560-81-5 2-<3-chloro-4-<(p-chlorophenyl)thio>-5-methylphenyl>-as-triazine-3,5(2H,4H)-dione 
• 53266-64-1 (2-{[3-Chloro-4-(4-chloro-phenylsulfanyl)-5-methyl-phenyl]-hydrazono}-3-ethoxycarbonylamino-3-oxo-propionyl)-carbamic acid ethyl ester 
• 40913-55-1 2-<3-chloro-4-<(p-chlorophenyl)thio>-5-methylphenyl>-6-carboxy-as-triazine-3,5(2H,4H)-dione 
• 78983-80-9 3-chloro-4-<(p-chlorophenyl)thio>-5-methylnitrobenzene 
• 53266-62-9 3-chloro-4-<(p-chlorophenyl)thio>-5-methylaniline 

Relevant articles and documents

Development of 2, 4-diaminoquinazoline derivatives as potent PAK4 inhibitors by the core refinement strategy

Upon analysis of the reported crystal structure of PAK4 inhibitor KY04031 (PAK4 IC50?=?0.790?μM) in the active site of PAK4, we investigated the possibility of changing the triazine core of KY04031 to a quinazoline. Using KY04031 as a starting

SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES

The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.

Transition metal catalysed cross-coupling between benzylic halides and aryl nucleophiles. Synthesis of some toxicologically interesting tetrachlorobenzyltoluenes

The aryl-benzyl cross-coupling in the presence of copper-, nickel- and palladium-catalysts has been investigated with a number of chlorine- and methyl-substituted arylmetal compounds ArM (M = MgBr, ZnCl) and (substituted) benzylic halides ArCH2X. The results have been applied in the selective synthesis of some toxicologically interesting tetrachlorobenzyltoluenes.