51738-10-4

Basic information

• Product Name: Benzene, 1-(2,2-dibromoethenyl)-4-nitro-
• CAS NO: 51738-10-4
• Molecular Formula: C8H5Br2NO2
• Molecular Weight: 306.941
• Mol File: 51738-10-4.mol
• Article Data: 34

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2,2-dibromoethenyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2,2-dibromoethenyl)-4-nitro-(51738-10-4)
• EPA Substance Registry System: Benzene, 1-(2,2-dibromoethenyl)-4-nitro-(51738-10-4)

Safety Data

• Hazardous Substances Data: 51738-10-4(Hazardous Substances Data)

Upstream product

• 42867-45-8 (dibromomethylene)triphenylphosphorane 
• 555-16-8 4-nitrobenzaldehdye 
• 558-13-4 carbon tetrabromide 
• 6310-10-7 4-nitrobenzaldehyde hydrazone 
• 619-73-8 4-nitrobenzyl chloride 
• 603-35-0 triphenylphosphine 
• 56506-90-2 (dibromomethyl)(triphenyl)phosphonium bromide 

Downstream Products

• 105072-35-3 2-(4-nitrophenyl)-1-(piperidin-1-yl)ethan-1-one 
• 50508-40-2 1-morpholino-2-(4-nitrophenyl)ethanone 
• 90405-67-7 N,N-dimethyl-2-(4-nitrophenyl)acetamide 
• 112030-58-7 2-(4-nitrobenzyl)-4,5-dihydro-1H-imidazole 
• 50507-86-3 Diethylamide of p-nitrophenylacetic acid 
• 86100-38-1 N-butyl-2-(4-nitrophenyl)acetamide 
• 1107616-68-1 β,β-bis(4-aminophenylethynyl)-4-nitrostyrene 
• 1428901-37-4 4-bromo-3-methyl-5-(4-nitrophenyl)-3-phenyl-3H-pyrazole 
• 1428901-46-5 4-bromo-5-(4-nitrophenyl)-3-phenyl-1H-pyrazole 
• 108011-31-0 (Z)-1-(2-bromo-2-phenylvinyl)-4-nitrobenzene 
• 1694-20-8 trans-4-nitrostilbene 
• 4309-66-4 p-amino-trans-stilbene 
• 2945-08-6 methyl (4-nitrophenyl)acetate 
• 35283-08-0 ethyl 3-(4-nitrophenyl)prop-2-ynoate 

Relevant articles and documents

A Radical-Initiated Fragmentary Rearrangement Cascade of Ene-Ynamides to [1,2]-Annulated Indoles via Site-Selective Cyclization

Straightforward access to [1,2]-annulated indoles, key substructures in natural products, is highly desirable yet challenging. Herein, a radical triggered fragmentary cyclization cascade reaction of ene-ynamides is presented, providing a rapid access into [1,2]-annulated indoles by an intermolecular radical addition, intramolecular cyclization, desulfonylative aryl migration, and site-selective C(sp2)-N cyclization sequence. DFT calculations support oxidation of N-centered radical species to cations prior to the C-N bond formation, followed by an unusual aza-Nazarov cyclization.

Pd-Catalyzed decarboxylative alkynylation of alkynyl carboxylic acids with arylsulfonyl hydrazides via a desulfinative process

In the presence of a Pd(ii)/P-ligand catalytic system, decarboxylative alkynylation of alkynyl carboxylic acids and arylsulfonyl hydrazides by desulfinative coupling could provide aryl alkynes in satisfactory yields by either judiciously selecting palladium catalysts or modulating phosphine ligands under mild conditions. The reported coupling reactions are very practical as they do not require the protection of inert gas or oxygen and are tolerant to many functional groups.

Na2S-mediated synthesis of terminal alkynes from: Gem -dibromoalkenes

The Na2S-mediated facile synthesis of terminal alkynes from gem-dibromoalkenes, at 20/40 °C under open flask conditions has been developed. Various precursors derived from heteroaromatic/aromatic/aliphatic aldehydes were found compatible. The reaction is proposed to proceed through the Fritsch-Buttenberg-Wiechell (FBW) rearrangement involving the corresponding vinyl carbene. Using mild reaction conditions with inexpensive Na2S·9H2O under air atmosphere has significant advantages over earlier routes.