51793-64-7

Basic information

• Product Name: Benzenemethanesulfinic acid, sodium salt
• Synonyms: 2,6-Dimethoxy-3H-pyrimidin-4-thion
• CAS NO: 51793-64-7
• Molecular Formula: C7H8O2S.Na
• Molecular Weight: 178.187
• Mol File: 51793-64-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenemethanesulfinic acid, sodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanesulfinic acid, sodium salt(51793-64-7)
• EPA Substance Registry System: Benzenemethanesulfinic acid, sodium salt(51793-64-7)

Safety Data

• Hazardous Substances Data: 51793-64-7(Hazardous Substances Data)

Usage

Uses

Sodium Phenylmethanesulfinate is used in preparation of (E)-1-phenyl-4-sulfonylbut-1-ene compounds.

Upstream product

• 67219-33-4 2-phenylmethanesulfonyl-benzothiazole 
• 66310-10-9 N-benzyl-2,4,6-triphenylpyridinium tetrafluoroborate 
• 100-46-9 benzylamine 
• 1939-99-7 benzenesulfonyl chloride 
• 19654-17-2 2-benzylthiobenzothiazole 
• 62381-90-2 2-(phenylmethylsulfinyl)pyridine N-oxide 

Downstream Products

• 20614-98-6 Methyl N-methyl-N--carbamat 
• 35145-12-1 Methyl-phenylmethanesulfonylmethyl-carbamic acid p-tolyl ester 
• 35145-11-0 Methyl-phenylmethanesulfonylmethyl-carbamic acid phenyl ester 
• 101657-26-5 1-Benzylsulfonyl-4,4-bis-<4-dimethylamino-phenyl>-1,2-dicyan-butadien-(1,3) 
• 100148-44-5 1,2-Bis-(benzylsulfonyl)-1,2-dicyan-ethen 
• 100148-37-6 1-Benzylsulfonyl-2-benzyl-1,2-dicyan-ethen 
• 10038-09-2 benzyl dichloromethyl sulfone 
• 139555-12-7 (E)-2-phenylethene-1-sulfonic acid 
• 7317-62-6 4-<2-Benzylsulfonyl-1,2-dicyan-vinyl>-N,N-dimethyl-anilin 
• 3012-37-1 benzyl thiocyanate 
• 100-52-7 benzaldehyde 
• 100-51-6 benzyl alcohol 
• 23670-27-1 Sodium; phenyl-methanethiosulfonate 
• 620-32-6 dibenzyl sulfone 

Relevant articles and documents

Sulfinates from Amines: A Radical Approach to Alkyl Sulfonyl Derivatives via Donor-Acceptor Activation of Pyridinium Salts

Synthetically versatile alkyl sulfinates can be prepared from readily available amines, using Katritzky pyridinium salt intermediates. In a catalyst-free procedure, primary, secondary, and benzylic alkyl radicals are generated by photoinduced or thermally induced single-electron transfer (SET) from an electron donor-acceptor (EDA) complex, and trapped by SO2 to generate sulfonyl radicals. Hydrogen atom transfer (HAT) from Hantzsch ester gives alkyl sulfinate products, which are used to prepare a selection of medicinal chemistry relevant sulfonyl-containing motifs.

Regio- and Enantioselective Preparation of Chiral Allylic Sulfones Featuring Elusive Quaternary Stereocenters

We describe here the first general asymmetric synthesis of sterically encumbered α,α-disubstituted allylic sulfones via Pd-catalyzed allylic substitution. The design and application of a new and highly efficient phosphoramidite ligand (L10) proved to be crucial, and a wide variety of challenging allylic sulfones featuring quaternary stereocenters could be obtained in good yields and with good to excellent levels of regio- and enantioselectivities under attractive process conditions. The developed methodology employs easily accessible chemical feedstock including racemic allylic precursors and sodium sulfinates. The utility of the method is further demonstrated by the synthesis of the sesquiterpene (?)-Agelasidine A.

Benzothiazole Sulfinate: A Sulfinic Acid Transfer Reagent under Oxidation-Free Conditions

Sulfinic acids are commonly encountered intermediates found in natural product synthesis and medicinal chemistry. However, because of high reactivity, instability, and harsh reaction conditions, they are difficult to synthesize. Herein we have developed an oxidation-free method to produce sulfinic acids and sulfinate salts using 2-sulfinyl benzothiazole (BTS). We have also demonstrated the synthetic usefulness by developing one-pot syntheses of sulfones and sulfonamides.