51795-98-3Relevant academic research and scientific papers
2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS
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Page/Page column 92, (2017/02/09)
The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N', C', A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.
Bent-core mesogens with an aromatic unit at the terminal position
Bajzíková, Kvetoslava,Svoboda, Ji?í,Novotná, Vladimíra,Pociecha, Damian,Gorecka, Ewa
supporting information, p. 4672 - 4679 (2017/07/10)
Bent-core liquid crystals with a naphthalene central unit and an aromatic ring at the terminal position of molecular tails were synthesised with the aim of enhancing nanosegregation. It was found that the length of the spacer between the rigid core and the terminal aromatic moiety had a profound influence on the liquid crystal polymorphism. The homologues with short spacers exhibited nematic and columnar phases, whereas the homologue with long spacers exhibited a tilted lamellar phase with a liquid-like in-plane order, indicating an unusual morphology of the densely packed toroidal objects. The morphology can be changed to twisted ribbons by small additives adsorbed on the membrane surface. This is the first example of twisted ribbons constructed by a lamellar system with no long-range in-plane order.
1-Phenoxyalkyl-4-[(N,N-disubstitutedamino)alkyl]piperazine derivatives as non-imidazole histamine H3-antagonists
Staszewski, Marek,Walczynski, Krzysztof
, p. 1287 - 1304 (2013/04/10)
In this study, a series of 1-phenoxyalkyl-4-[(N,N-disubstitutedamino)alkyl] piperazine derivatives has been prepared and in vitro tested as H 3-receptor antagonists (electrically evoked contraction of the guinea pig jejunum). All compounds inve
Homologs of idoxifene: Variation of estrogen receptor binding and calmodulin antagonism with chain length
Hardcastle, Ian R.,Rowlands, Martin G.,Grimshaw, Rachel M.,Houghton, John,Jarman, Michael,Sharff, Andrew,Neidle, Stephen
, p. 999 - 1004 (2007/10/03)
A series of homologs of idoxifene [1a, (E)-1-[4-(N- pyrrolidinoethoxy)phenyl]-1-(4-iodophenyl)-2-phenyl-1-butene] and selected homologs of 4-iodotamoxifen [2a, (E)-1-[4-[(N-dimethylamino)ethoxy]phenyl]- 1-(4-iodophenyl)-2-phenyl-1-butene] with the side ch
Octakationische Cyclophane: Bindung von ATP und anderen anionischen Gastmolekuelen in Wasser
Menger, Fredric M.,Catlin, Kelly K.
, p. 2330 - 2333 (2007/10/03)
Keywords: ATP; Cyclophane; Makrocyclen; Supramolekulare Chemie
Aminodesoxy-1.4;3.6-dianhydrohexitol nitrates and pharmaceutical composition
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, (2008/06/13)
Aminodesoxy-1.4;3.6-dianhydrohexitol nitrates of the general formula I, STR1 wherein R1 and R2 possess the meanings given in claim 1, as well as their pharmacologically acceptable acid-addition salts; processes for the preparation of said compounds, and pharmaceutical compositions containing at least one of said compounds.
