51806-98-5

Basic information

• Product Name: 2-aminopropanenitrile
• CAS NO: 51806-98-5
• Molecular Formula: C₃H₆N₂
• Molecular Weight: 70.094
• Mol File: 51806-98-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-aminopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aminopropanenitrile(51806-98-5)
• EPA Substance Registry System: 2-aminopropanenitrile(51806-98-5)

Safety Data

• Hazardous Substances Data: 51806-98-5(Hazardous Substances Data)

Usage

Main properties

Chemical formula: C3H7N
Physical state: Colorless liquid or solid
Uses: Synthesis of organic compounds and pharmaceuticals, production of resins and adhesives, potential industrial applications as a building block in the production of polymers, plastics, and other materials
Toxicity: Toxic and harmful if it comes into contact with the skin or is ingested

Specific content

Chemical name: 2-Aminopropanenitrile
Other names: Alpha-aminopropionitrile, 2-APN
Organic compound: Yes
Potential forms: Colorless liquid or solid
Uses in synthesis: Various organic compounds and pharmaceuticals
Uses in production: Resins and adhesives, potential industrial applications as a building block in the production of polymers, plastics, and other materials
Toxicity: Toxic and harmful if it comes into contact with the skin or is ingested

Upstream product

• 107-16-4 glycolonitrile 
• 7732-18-5 water 
• 107-13-1 acrylonitrile 
• 67337-69-3 methyl-5 hydantoine 
• 78-97-7 2-hydroxy-propionitrile 
• 151-50-8 potassium cyanide 
• 75-07-0 acetaldehyde 
• 2869-25-2 2,2'-iminodipropionitrile 

Downstream Products

• 19861-71-3 N-(1-cyanoethyl)acetamide 
• 2869-25-2 2,2'-iminodipropionitrile 
• 57768-55-5 meso-bis-(1-cyano-ethyl)-amine 
• 57355-08-5 3,5,6-trimethyl-1,2-dihydropyrazin-2-one 
• 19838-07-4 3-methylpyrazin-2(1H)-one 
• 32464-52-1 3-methyl-1-oxy-5-phenyl-pyrazin-2-ylamine 
• 78-90-0 1,2-diaminopropan 
• 302-72-7 rac-Ala-OH 
• 51806-96-3 α-(N-γ-DL-Glutamyl)-amino-propionitril 
• 142-04-1 aniline hydrochloride 
• 313476-20-9 N-(1-Cyanoethyl)-7-[3-(4-cyanophenoxy)-2-hydroxypropyl]-3,7-diaza-bicyclo[3.3.1]nonane-3-carboxamide 
• 1194506-74-5 C₁₇H₁₂ClN₃ 
• 64843-47-6 D,L-(1-cyanoethyl)carbamothioic acid, S-phenyl ester 

Relevant articles and documents

Synthesis of aldehydic ribonucleotide and amino acid precursors by photoredox chemistry

Light work: UV irradiation of a system formed by adding copper(I) cyanide to an aqueous solution of glycolonitrile, sodium phosphate, and hydrogen sulfide efficiently generates aldehyde precursors to the building blocks of RNA and proteins. Copyright

Chemie der α-Aminonitrile. 1. Mitteilung. Einleitung und Wege zu Uroporphyrinogen-octanitrilen

Chemistry of α-Aminonitriles I: Introduction and Pathways to Uroporphyrinogen-octanitriles.An introduction to experimental studies on the chemistry of α-aminonitriles potentially relevant to the problems of prebiotic chemistry is presented.The framework of conditions wherein the investigations is chosen to be carried out implies both molecular oxygen and - whenever feasible - water to be excluded from reaction conditions.This study focusses on 2-amino-2-propenenitrile (3) (Scheme 6) as central starting material of reaction sequences which aim at the nitrile forms of proteinogenic amino acids as well as at the aza forms of building blocks of biological cofactor molecules as their targets (Scheme 5).Schemes 13, 16, 23 as well as 25, and 26 summarize reaction sequences by which 3 is tranformed within the definied framework of conditions into the thermodynamic (statistically controlled) mixture of the four isomeric uroporphyrinogen-octanitriles 57-60.HPLC's of such mixtures document the dominance of the least symmetrical isomer whose constitutional pattern of peripheral substituents happens to be the one present in all biological porphinoids.Preparative procedures for the synthesis of 3 (Scheme 9), the β,β-disubstututed pyrrol-nitriles 30, 53, and 54 (Scheme 19) as well as the porphyrinogen-octakis(propionitrile) and -octakis(acetonitrile) 65 and 66, respectively (Scheme 24) are given.