19838-07-4

Usage

Uses

Used in Food and Beverage Industry:
2-Hydroxy-3-methylpyrazine is used as a flavoring agent for its nutty and earthy aroma, enhancing the taste and aroma of various food and beverage products.
Used in Pharmaceutical Production:
2-Hydroxy-3-methylpyrazine is utilized in the production of pharmaceuticals, contributing to the development of new drugs and medicinal compounds.
Used in Perfumes and Personal Care Products:
As a fragrance ingredient, 2-Hydroxy-3-methylpyrazine is used in perfumes and personal care products to provide a unique and pleasant scent.

InChI:InChI=1/C5H6N2O/c1-4-5(8)7-3-2-6-4/h2-3H,1H3,(H,7,8)

Upstream product

• 131543-46-9 Glyoxal 
• 4726-84-5 alanine amide 
• 109-08-0 2-Methylpyrazine 
• 873-67-6 benzonitrile oxide 
• 67-56-1 methanol 
• 56-23-5 tetrachloromethane 
• 35320-22-0 D-alaninamide 
• 80222-96-4 2-aminopropanamide hydrochloride 
• 51806-98-5 2-aminopropanenitrile 

Downstream Products

• 95-58-9 2-chloro-3-methylpyrazine 
• 120984-76-1 2-bromo-3-methyl-pyrazine 
• 100047-56-1 5-bromo-3-methyl-1H-pyrazin-2-one 
• 65735-15-1 2-Cyano-3-methylpyrazine 
• 104893-52-9 3-methylpyrazine-2-carboxamide 
• 58139-08-5 2-iodo-3-methyl-pyrazine 
• 100047-56-1 5-bromo-3-methylpyrazin-2-ol 
• 23936-11-0 3-methylpiperazin-2-one 
• 212608-90-7 N¹-[4-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)-butyl]-3-methyl-2-pyrazinone 

Relevant academic research and scientific papers

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

Aromatic amino ethers as pain relieving agents

The present invention relates to compounds of formula (I), STR1 wherein A is an optionally substituted phenyl naphthyl, pyridyl, pyrazinyl, pyridazinyl, pyrimidyl, thienyl, thiazolyl, oxazolyl, thiadiazolyl having at least two adjacent ring carbon atoms or a bicyclic ring system, provided that the --CH(R3)N(R2)B--R1 and --OCH(R4 --)--D linking groups arm positioned in a 1,2 relationship to one another on ring carbon atoms and the ring atom positioned ortho to the --OCHR4 -- linking group (and therefore in the 3-position relative to the --CHR3 NR2 -- linking group) is not substituted; B is an optionally substituted ring system; D is an optionally substituted ring system; R1 is a variety of group as defined in the description; R2 is hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, phenylC1-3 alkyl or 5- or 6-membered heteroarylC1-3 alkyl; R3 is hydrogen or C1-4 alkyl; R4 is hydrogen or C1-4 alkyl; and N-oxides of NR2 where chemically possible; and S-oxides of sulphur containing rings were chemically possible; and pharmaceutically acceptable salts and in vivo hydrolysable esters and amides thereof. Process for their preparation, intermediates in theirpreparation, their use as therapeutic agents and pharmaceutical compositions containing them.

Reaction of Diazines and their Benzo derivatives with Benzonitrile oxide

The reaction of diazines 1 and benzodiazines 2 with benzonitrile oxide in refluxing benzene affords regio, site and stereospecific cycloadducts to the diazine ring and/i43or products derived from them.

PYRAZINES, PYRIMIDINES AND PYRIDAZINES USEFUL IN THE TREATMENT OF SENILE DEMENTIA

The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic ring system; and independently substituted on each of the other ring carbon atoms with a substituent of low lipophilicity or a hydrocarbon substituent; which compounds stimulate central muscarinic acetylcholine receptors and therefore are useful in the treatment of neurological and mental illnesses.