5195-30-2

Upstream product

• 242483-39-2 2-methyl-4-phenyl-butyryl chloride 
• 86568-38-9 cuprate de methyle 
• 5195-17-5 2-methyl-3-oxo-2-phenethyl-butyric acid ethyl ester 
• 40463-08-9 2,2-dimethyl-3-(2-phenylethyl)oxirane 
• 104-53-0 3-phenyl-propionaldehyde 
• 2550-26-7 4-Phenyl-2-butanone 
• 289680-83-7 1-chloro-4-phenyl-1-(p-tolylsulfinyl)-2-butanol 
• 1949-41-3 2-methyl-4-phenylbutanoic acid 
• 5337-63-3 ethyl 2-(2-phenylethyl)acetoacetate 
• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 103-63-9 1-phenyl-2-bromoethane 

Downstream Products

• 36748-51-3 2,3-Dimethyl-5-phenyl-2-pentanol 
• 36748-82-0 3-methyl-5-phenyl-2-pentanol 

Relevant academic research and scientific papers

A Catalytic Intermolecular Formal Ene Reaction between Ketone-Derived Silyl Enol Ethers and Alkynes

A catalytic formal ene reaction between ketone-derived silyl enol ethers and terminal alkynes is described. This transformation is uniquely capable of bimolecular assembly of 2-siloxy-1,4-dienes and can be used to access β,?-unsaturated ketones containing quaternary carbons in the α-position.

Chemoenzymatic Approach toward the Pure Enantiomers of 2-Methyl-1,3-propanediol Mono(p-Methoxybenzyl Ether)

In a route towards the enantiomerically pure 2-methylpropane-1,3-diol mono(p-methoxybenzyl ether), which is an important starting material for natural product synthesis, a kinetic resolution approach by means of lipase-catalyzed hydrolysis as well as acyl

Cyclialkylation of arylalkyl epoxides with solid acid catalysts

Solid acids, such as zeolites and clays, catalyse the intramolecular hydroxyalkylation (cyclialkylation) of several arylalkyl epoxides in moderate to excellent conversions and selectivities. The use of solid acids in these cyclialkylations provides a cleaner, better alternative to conventional Lewis and Bronsted acids, enabling a more facile workup of reaction mixtures and, in several cases, better selectivities.

New Method for Generation of β-Oxido Carbenoid via Ligand Exchange Reaction of Sulfoxides: A Versatile Procedure for One-Carbon Homologation of Carbonyl Compounds

A new procedure for one-carbon homologation of carbonyl compounds is described.The method is based on the rearrangement of β-oxido carbenoid which is generated via the ligand exchange reaction of the sulfinyl group of α-chloro β-hydroxy sulfoxide with tert-butyllithium.Addition of the carbanion of aryl 1-chloroalkyl sulfoxides to carbonyl compounds gave the adducts in good yields.The β-oxido carbenoid rearrangement of the adducts gave one-carbon homologated carbonyl compounds having an α-alkyl substituent.A similar reaction of the adducts derived from carbonyl compounds with chloromethyl p-tolyl sulfoxide yielded a procedure for a methylene insertion.The stereochemistry of the β-oxido carbenoid rearrangenment is also discussed.