5337-63-3

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-phenethylacetoacetate is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its versatile chemical structure allows for the development of new drugs and therapeutic agents.
Used as a Flavoring and Fragrance Agent:
Ethyl 2-phenethylacetoacetate is used as a flavoring agent in the food and beverage industry, adding a pleasant floral note to various products. Its unique aroma also makes it a popular choice for use in the fragrance industry, where it can be incorporated into perfumes, colognes, and other scented products.
Used in Medicinal Research:
Due to its potential anti-inflammatory and anti-oxidant properties, Ethyl 2-phenethylacetoacetate is a subject of interest in medicinal research. Scientists are exploring its potential applications in the development of new treatments for various diseases and conditions.
Used in Cosmetics and Personal Care Products:
Ethyl 2-phenethylacetoacetate's pleasant floral scent and potential anti-inflammatory properties make it a valuable ingredient in cosmetics and personal care products. It can be used in formulations for skincare, haircare, and other beauty products to provide a pleasant aroma and potential therapeutic benefits.

InChI:InChI=1/C14H18O3/c1-3-17-14(16)13(11(2)15)10-9-12-7-5-4-6-8-12/h4-8,13H,3,9-10H2,1-2H3

Upstream product

• 17376-04-4 2-phenethyl iodide 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 103-63-9 1-phenyl-2-bromoethane 
• 141-97-9 ethyl acetoacetate 
• 60-12-8 2-phenylethanol 

Downstream Products

• 3360-41-6 4-phenyl-butan-1-ol 
• 2235-83-8 5-phenyl-2-pentanone 
• 100256-98-2 2-(1-hydroxy-ethyl)-4-phenyl-butyric acid 
• 5469-48-7 phenethyl-fumaric acid 
• 6683-92-7 1-phenylpentan-2-one 
• 82586-61-6 ethyl 2-bromo-4-phenylbutanoate 
• 107575-75-7 3-Methyl-4-phenethyl-4H-isoxazol-5-one 
• 154388-86-0 β-Phenethylacetessigsaeureethylester-dioxolan 
• 210180-76-0 3-Oxo-2-(2-oxo-2-phenyl-ethyl)-2-phenethyl-butyric acid ethyl ester 
• 6279-88-5 1-methyl-3,4-dihydronaphthalene-2-carboxylic acid 
• 4488-44-2 1-methyl-2-naphthoic acid 
• 501658-19-1 2-imido-6-methyl-5-(2-phenylethyl)uracil 
• 357212-07-8 7-hydroxy-3-phenethyl-4-methyl-2H-chromen-2-one 
• 294865-14-8 3-(trans-4-propylcyclohexyl)-6-(2-phenylethyl)cyclohex-2-en-1-one 

Relevant academic research and scientific papers

NO Donor coumarin furoxan conjugates and pharmaceutical use thereof

The invention belongs to the technical field of chemical pharmacy. Experiments prove that the furoxan conjugate has good water 3 - solubility, has excellent inhibitory activity on the growth of sensitive human tumor cells and resistant tumor cells, and NO

Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor

We optimized the structure of an active metabolite (1) of WAY-123783, which was obtained from mouse urine after oral administration, to improve selectivity for SGLT2 and oral bioavailability. O-glucoside derivative 24 (remogliflozin etabonate) was subsequently identified as a potent, highly selective, and orally available SGLT2 inhibitor.

Silver-Catalyzed Olefination of Acetals and Ketals with Diazoesters to β-Alkoxyacrylates

The first silver-catalyzed reaction of acetals or ketals with diazoesters leading to trisubstituted or tetrasubstituted β-alkoxyacrylates is now reported. A broad range of acetals and ketals bearing different substituents is compatible with this protocol and thus provides an attractive approach for the synthesis of complex β-alkoxyacrylates. The power of this method was further demonstrated by the successful synthesis of picoxystrobin, which is one of the most popular agricultural fungicides commercialized by Dupont.

NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR

[Problem] The present invention addresses the problem of providing a novel compound. The present invention also addresses the problem of providing an OCT3 detection agent or an OCT3 activity inhibitor, which comprises the novel compound. [Solution] A compound represented by formula (A), a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof. ????????R1-R2-R3-R4?????(A)

4H- [1, 2, 4] TRIAZOLO [5, 1 -B] PYRIMIDIN-7 -ONE DERIVATIVES AS CCR2B RECEPTOR ANTAGONISTS

The present invention relates to novel compounds for use in the compositions, to processes for their preparation, to intermediates useful in their preparation and to their use as therapeutic agents. The present invention also relates to pharmaceutical com

2-OXO-2H-CHROMENE COMPOUNDS

Compounds of structural formula (1) modulate CRTH2 activity and are of utility in, for example, respiratory diseases formula (1): in which: A represents a direct bond, an optionally substituted alkylene or alkenylene group, or a group of formula Z-(optionally substituted)alkylene; B represents a direct bond, an optionally substituted alkylene or alkenylene group, or a group of formula Z-(optionally substituted)alkylene or (optionally substituted)alkylene-Z; Z represents an oxygen atom, an NH or N-alkyl group, or a group of formula S(O)n, in which n = 0 to 2; X represents a carboxylic acid, tetrazole, 3-hydroxyisoxazole, hydroxamic acid, phosphinate, phosphonate, phosphonamide, sulfonic acid or a group of formula C(=O)NHSO2W or SO2NHC(=O)W; W represents an optionally substituted aryl or heteroaryl group or an optionally substituted alkyl or cycloalkyl group; Y represents an optionally substituted phenyl or 5- or 6-membered heteroaryl group, Ra, Rb, and Rc independently represent hydrogen, acyl, alkoxy, alkoxycarbonyl, alkylamino, alkylsulfinyl, alkylsulfonyl, alkylthio, -NH2, aminoalkyl, hydroxyalkyl, alkoxyalkyl, arylalkyl, cyano, dialkylamino, halo, haloalkoxy, haloalkyl, alkyl, alkenyl, -OH, optionally substituted aryl, optionally substituted heteroaryl, heterocycloalkyl, aminoacyl, aminosulfonyl, acylamino, sulfonylamino, heteroarylalkyl, cyclic amino, aryloxy, heteroaryloxy, arylalkyloxy or heteroarylalkyloxy.

3,4-dihydro-2-naphthamide derivatives as selective dopamine D3 ligands

The invention relates to 3,4-dihydro-2-naphthamide derivatives of formula (I), pharmaceutical compositions containing them and their therapeutic applications as partial agonists or antagonists of the dopamine D3 receptor for the treatment of neuropsychological disorders.

METHOD FOR PURIFYING PYRUVIC ACID COMPOUNDS

The present invention is directed to a method for purifying pyruvic acid compounds, which method comprises reacting a pyruvic acid compound of general formula (I): wherein R1is an optionally substituted lower alkyl group, a lower alkenyl group,

Photochemistry of substituted cyclic enones. Part 11. Synthesis and photophysics of 5-arylalkyl-3-phenylcyclopentenones

The photophysical properties of 3-phenyl-5-[2-(1-naphthyl)ethyl]cyclopent-2-enone and 5-[2-(1-naphthyl)-methyl]-3-phenylcyclopent-2-enone have been compared with those of their constituent alkylated chromophores 1-ethylnaphthalene, 3-phenyl-5-(2-phenyleth