52107-87-6

Usage

Uses

Used in Pharmaceutical Industry:
4-IODO-3-METHYLBENZOIC ACID is used as a key building block in the synthesis of various drugs and pharmaceutical intermediates, contributing to the development of new medicinal compounds.
Used in Dye Production:
4-IODO-3-METHYLBENZOIC ACID is utilized as a precursor in the production of dyes, playing a crucial role in the creation of colorants for various applications.
Used in Fragrance Industry:
4-IODO-3-METHYLBENZOIC ACID is employed as a component in the synthesis of fragrances, adding to the complexity and variety of scents in the market.
Used in Agrochemicals:
4-IODO-3-METHYLBENZOIC ACID is used in the development of agrochemicals, potentially contributing to the production of pesticides and other agricultural chemicals to enhance crop protection and yield.
Safety Note:
Due to its classification as a hazardous substance, 4-IODO-3-METHYLBENZOIC ACID requires careful handling and disposal in accordance with established safety guidelines to prevent adverse effects on health and the environment.

InChI:InChI=1/C8H7IO2/c1-5-4-6(8(10)11)2-3-7(5)9/h2-4H,1H3,(H,10,11)

Upstream product

• 4214-28-2 1-iodo-2,4-dimethylbenzene 
• 7697-37-2 nitric acid 
• 2486-70-6 4-amino 3-methylbenzoic acid 
• 7681-65-4 copper(I) iodide 
• 866996-02-3 4-ethyl-1-iodo-2-methyl-benzene 
• 52107-80-9 1-(4-iodo-3-methyl-phenyl)-ethanone 
• 78881-21-7 4-amino-3-methylbenzonitrile 

Downstream Products

• 5471-81-8 methyl 4-iodo-3-methylbenzoate 
• 959632-18-9 (4-iodo-3-methylphenyl)methanol 
• 171049-14-2 lotrafiban 
• 360059-34-3 tert-butyl 4-iodo-3-methylaminomethylbenzoate 
• 1026885-57-3 3-{[(2-amino-3-carboxy-propionyl)-methyl-amino]-methyl}-4-iodo-benzoic acid tert-butyl ester 
• 360059-35-4 (S)-tert-butyl 3-(N-Fmoc-aspartate-β-methyl ester-N-methyl)-amino-methyl-4-iodo-benzoate 
• 299956-67-5 (4-iodo-3-methyl-phenyl)-acetic acid 
• 444068-62-6 4-(5-FORMYL-FURAN-2-YL)-3-METHYL-BENZOIC ACID 

Relevant academic research and scientific papers

Acidity of benzoic acids bearing the (CO)5Cr=CN(CH 3)2 group

Benzoic acids 2a and 2b, bearing the (CO)5Cr=CN(CH 3)2 group in the p- and m-position, and the corresponding benzoic acids 2c and 2d, in which the rotation of the aminocarbene moiety was blocked by the presence of a methyl group, were prepared together with the corresponding N,N-dimethylamido acids 3a-d. The measurement of pKa values in EtOH and DMF revealed that the (CO)5Cr=CN(CH 3)2 group is a very weak electron acceptor (δp = 0; δm = 0.14). The restriction of the rotation of the aminocarbene moiety did not significantly influence its electronic properties. The obtained results are in accordance with earlier findings that the relatively strong acidity of carbene complexes bearing hydrogens at the ±-position to the carbene atom is due to the resonance stabilization of the anion.

RXR-agonist polycyclic aromatic compounds, pharmaceutical/cosmetic compositions comprising said compound and uses thereof

Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds having the structural formula (I): wherein Ar is a radical having one of the formulae (a)-(e): which are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders are provided. In particular, based on their RXR-agonist activity, these compounds may be used to treat noninsulin-dependent diabetes mellitus (NIDDM) and obesity.

Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof

Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (1): STR1 in which X is one of the radicals: STR2 and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof

Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): STR1 wherein Ar is a radical having one of the formulae (a)-(i): STR2 and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.