5216-46-6

Basic information

• Product Name: Benzene, 1,1'-(2-chloroethylidene)bis-
• CAS NO: 5216-46-6
• Molecular Formula: C14H13Cl
• Molecular Weight: 216.71
• Mol File: 5216-46-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(2-chloroethylidene)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(2-chloroethylidene)bis-(5216-46-6)
• EPA Substance Registry System: Benzene, 1,1'-(2-chloroethylidene)bis-(5216-46-6)

Safety Data

• Hazardous Substances Data: 5216-46-6(Hazardous Substances Data)

Upstream product

• 623-46-1 1,2-dichloro-2-ethoxyethane 
• 71-43-2 benzene 
• 119-61-9 benzophenone 
• 593-71-5 Chloroiodomethane 
• 117-34-0 2,2-diphenylacetic acid 
• 57561-93-0 2,2-diphenyldiazoethane 
• 2971-22-4 2,2-bis(phenyl)-1,1,1-trichloroethane 
• 1883-32-5 2,2-diphenyl ethanol 
• 98-07-7 Benzotrichlorid 

Downstream Products

• 5586-79-8 1,1-Diphenyl-2-morpholino-aethan 
• 73473-75-3 2-chloro-1,1-bis-(4-nitro-phenyl)-ethane 
• 7647-01-0 hydrogenchloride 
• 588-59-0 stilbene 
• 10605-46-6 1,1-bis(4-nitrophenyl)ethylene 
• 530-48-3 1,1-Diphenylethylene 
• 36171-54-7 C₂₉H₂₈ 
• 4541-89-3 2-chloro-1,1-diphenylethene 
• 612-00-0 1,1'-ethylidenebis-benzene 
• 1483-64-3 1,1,4,4-tetraphenyl-butane 
• 20017-67-8 3,3-diphenylpropan-1-ol 
• 41976-80-1 (2-methoxyethane-1,1-diyl)dibenzene 
• 18834-21-4 (2,2’-diphenylethyl)triphenylsilane 
• 7647-54-3 N,N-dimethyl-2,2-diphenyl-ethyl-1-amine 

Relevant articles and documents

Chemoselective Homologation-Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into (n+1)-Halomethyl-Alkanes

The sequential installation of a carbenoid and a hydride into a carbonyl, furnishing halomethyl alkyl derivatives, is reported. Despite the employment of carbenoids as nucleophiles in reactions with carbon-centered electrophiles, sp3-type alkyl halides remain elusive materials for selective one-carbon homologations. Our tactic levers on using carbonyls as starting materials and enables uniformly high yields and chemocontrol. The tactic is flexible and is not limited to carbenoids. Also, diverse carbanion-like species can act as nucleophiles, thus making it of general applicability.

Triphosgene-amine base promoted chlorination of unactivated aliphatic alcohols

Unactivated α-branched primary and secondary aliphatic alcohols have been successfully transformed into their corresponding alkyl chlorides in high yields upon treatment with a mixture of triphosgene and pyridine in dichloromethane at reflux. These mild chlorination conditions are high yielding, stereospecific, and well tolerated by numerous sensitive functionalities. Furthermore, no nuisance waste products are generated in the course of the reactions.

The conversion of alcohols to halides using a filterable phosphine source

The conversion of primary and secondary alcohols to chlorides and bromides using 1,2-bis(diphenylphosphino)ethane (diphos) is described. Use of this reagent in lieu of the typical triphenylphosphine-carbontetrahalide complex provides a facile means of purifying the desired halide from the phosphine-oxide byproduct.