52177-10-3Relevant articles and documents
Heterocyclic derivatives as well as pharmaceutical compositions and application thereof
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Paragraph 0145; 0148; 0149, (2021/05/26)
The invention discloses novel heterocyclic derivatives shown in a formula I, a formula II and a formula III, pharmaceutical compositions containing the heterocyclic derivatives and application of the heterocyclic derivatives in preparation of drugs for preventing and/or treating indications related to proton pump inhibition regulation. The heterocyclic derivatives disclosed by the invention are strong in drug effect and long in half-life period, are ideal efficient proton pump inhibitors, and can be used for treating or preventing diseases or diseases needing proton pump inhibition effect regulation, such as ulcer, esophagitis, gastritis, gastroesophageal reflux, helicobacter pylori infection, gastric cancer and the like.
Gold catalysis coupled with visible light stimulation: Syntheses of functionalized indoles
Cai, Shunyou,Yang, Kai,Wang, David Zhigang
supporting information, p. 2606 - 2609 (2014/06/09)
A judicious combination of Au-catalysis and synergistic visible-light stimulation formulates an exceptionally simple and mild reaction system capable of directly coupling anilines and alkynes to form multifunctionalized indoles.
SYNTHESIS OF INDOLES FROM PYRIDINIUM SALTS 5. SECONDARY AMINES IN THE REACTION OF 3-NITROPYRIDINIUM SALTS WITH ACETONE
Yurkovskaya, M. A.,Afanas'ev, A. Z.,Chertkov, V. A.,Bundel', Yu. G.
, p. 1000 - 1008 (2007/10/02)
The use of secondary amines in the reaction of 3-nitropyridinium salts with acetone makes it possible to isolate stable intermediates in the formation of indoles - (o-N,N-dialkylaminobenzyl)ketones - and to observe new reaction pathways - the formation of bisindolylpropanes and p-nitroanilines.