52191-71-6

Basic information

• Product Name: 4,4'-Biquinoline, 2,2'-dimethyl-
• Synonyms: 4,4'-Biquinoline,2,2'-dimethyl
• CAS NO: 52191-71-6
• Molecular Formula: C20H16N2
• Molecular Weight: 284.36
• Mol File: 52191-71-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4,4'-Biquinoline, 2,2'-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-Biquinoline, 2,2'-dimethyl-(52191-71-6)
• EPA Substance Registry System: 4,4'-Biquinoline, 2,2'-dimethyl-(52191-71-6)

Safety Data

• Hazardous Substances Data: 52191-71-6(Hazardous Substances Data)

Upstream product

• 10222-49-8 4-chloro-2-methylquinoline 
• 99361-09-8 4-iodo-2-methylquinoline 
• 5764-82-9 bromo(2-ethoxy-2-oxoethyl)zinc 
• 50488-45-4 2-methyl-4-quinolylgold(I) 
• 106-38-7 para-bromotoluene 
• 4295-06-1 4-chloro-2-methylquinoline 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 24398-88-7 ethyl 3-bromobenzoate 
• 91-63-4 2-methylquinoline 

Relevant articles and documents

Electrocatalytic Oxidative Coupling of Methylquinolines on TEMPO-modified Graphite Felt Electrodes

2- and 4-Methylquinolines were oxidized to 2,2'-dimethyl-4,4'-biquinolyl and 4,4'-dimethyl-2,2'-biquinolyl, respectively, both in ca. 94percent isolated yield and ca. 90percent current efficiency on a graphite felt electrode coated with a thin poly(acrylic acid) layer containing 4-amino-2,2,6,6-tetramethylpiperidinyl-1-oxyl (4-amino-TEMPO).The reaction proceeds via electrocatalytic oxidation of the modified-TEMPO species.The electrode was not inactivated during electrolysis and could be used repeatedly.

A Convenient Synthetic Route to bis-Heteroaromatic and bis-Heterocyclic Compounds Promoted by Liganded Nickel Complex Reducing Agents.

A number of nitrogen, sulfur or oxygen containing bis-heteroaromatic or bis-heterocyclic derivatives have been synthesized in good to excellent yields by homocoupling of the corresponding halogenated compounds in the presence of liganded (triphenylphosphine or 2,2'-bipyridine) nickel Complex Reducing Agents in THF or DME at 63 deg C.

ACTIVATION OF REDUCING AGENTS. SODIUM HYDRIDE CONTAINING COMPLEX REDUCING AGENTS 23. SYMMETRICAL COUPLING OF NITROGEN-CONTAINING HETEROCYCLIC HALIDES

The preparation of NiCRA (NaH-tBuONa-Ni(OAc)2) in the presence of PPh3 leads to a reagent (termed NiCRA-PPh3) which is shown to be one of the most efficient Ni containing reagents reported so far for the homocoupling of heteroaromatic halides.