52192-32-2

Upstream product

• 2212-75-1 N₂-[(benzyloxy)carbonyl]-L-lysine 
• 127-09-3 sodium acetate 
• 657-27-2 L-Lysine hydrochloride 
• 14511-39-8 2(S)-2-amino-6-(benzylideneamino)hexanoic acid 
• 64-19-7 acetic acid 
• 52192-22-0 6-acetoxy-2-amino-hexanoic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 519156-50-4 (S)-4-But-3-enyl-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 519156-49-1 (S)-4-(4-Acetoxy-butyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 503145-83-3 3-[(S)-6-acetoxy-2-(benzyloxycarbonyl)aminohexanoyl]-1,3-thiazolidine 
• 178734-93-5 Toluene-4-sulfonic acid (S)-5-benzyloxycarbonylamino-5-(2,6-dimethyl-phenylcarbamoyl)-pentyl ester 
• 178734-92-4 [(S)-1-(2,6-Dimethyl-phenylcarbamoyl)-5-hydroxy-pentyl]-carbamic acid benzyl ester 
• 154061-64-0 (2S)-2-<(Benzyloxycarbonyl)amino>-6-hydroxyhexanoic acid methyl ester 
• 27262-40-4 (S)-2',6'-pipecoloxylidide 
• 27262-47-1 levobupivacaine 
• 35677-83-9 methyl (S)-pipecolinate 
• 790302-14-6 (S)-2-{[(2S,3S)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester 
• 790302-06-6 (2S,3S)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester 
• 790302-05-5 (S)-3-Benzyloxycarbonylamino-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester 
• 790302-30-6 (S)-2-[((2S,3S)-3-Benzyloxycarbonylamino-7-hydroxy-2-methyl-heptanoyl)-methyl-amino]-3-methyl-butyric acid methyl ester 
• 790302-04-4 (S)-7-Acetoxy-3-benzyloxycarbonylamino-heptanoic acid methyl ester 

Relevant academic research and scientific papers

Stereocontrolled synthesis of onchidins

(Chemical Equation Presented) The first total synthesis of a molecule possessing the stereochemistry proposed for onchidin is described. The structure synthesized appears to be different from that of the marine natural product.

THIAZOLIDINE DERIVATIVE AND MEDICINAL USE THEREOF

A thiazolidine derivative represented by the formula (I) wherein each symbol is as defined in the specification, and a pharmaceutically acceptable salt thereof exhibit a potent DPP-IV inhibitory activity, and can be provided as an agent for the prophylaxis or treatment of diabetes, an agent for the prophylaxis or treatment of obesity and the like.

N-METHYL AMINO ACIDS

The present invention relates to a compound of formula (I) or (II), processes for preparing them, peptides including them and kits involving them.

Stereospecific synthesis of the anaesthetic levobupivacaine

Enantiomerically pure (S)-bupivacaine is synthesized from the chiral pool using cheap and readily available (S)-lysine. The key steps in this efficient synthesis include an oxidative de-amination and stereospecific ring closure to form the pipecolamide core structure.