52192-32-2

Upstream product

• 52192-22-0 6-acetoxy-2-amino-hexanoic acid 
• 501-53-1 benzyl chloroformate 
• 2212-75-1 N₂-[(benzyloxy)carbonyl]-L-lysine 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 
• 14511-39-8 2(S)-2-amino-6-(benzylideneamino)hexanoic acid 
• 657-27-2 L-Lysine hydrochloride 

Downstream Products

• 178734-91-3 Acetic acid (S)-5-benzyloxycarbonylamino-5-(2,6-dimethyl-phenylcarbamoyl)-pentyl ester 
• 790302-03-3 Acetic acid (S)-5-benzyloxycarbonylamino-7-diazo-6-oxo-heptyl ester 
• 790302-24-8 (S)-3-Benzyloxycarbonylamino-7-hydroxy-heptanoic acid methyl ester 
• 790302-04-4 (S)-7-Acetoxy-3-benzyloxycarbonylamino-heptanoic acid methyl ester 
• 790302-30-6 (S)-2-[((2S,3S)-3-Benzyloxycarbonylamino-7-hydroxy-2-methyl-heptanoyl)-methyl-amino]-3-methyl-butyric acid methyl ester 
• 790302-05-5 (S)-3-Benzyloxycarbonylamino-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester 
• 790302-06-6 (2S,3S)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester 
• 790302-14-6 (S)-2-{[(2S,3S)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester 
• 35677-83-9 methyl (S)-pipecolinate 
• 27262-47-1 levobupivacaine 
• 27262-40-4 (S)-2',6'-pipecoloxylidide 
• 154061-64-0 (2S)-2-<(Benzyloxycarbonyl)amino>-6-hydroxyhexanoic acid methyl ester 
• 178734-92-4 [(S)-1-(2,6-Dimethyl-phenylcarbamoyl)-5-hydroxy-pentyl]-carbamic acid benzyl ester 
• 178734-93-5 Toluene-4-sulfonic acid (S)-5-benzyloxycarbonylamino-5-(2,6-dimethyl-phenylcarbamoyl)-pentyl ester 

Relevant academic research and scientific papers

Stereocontrolled synthesis of onchidins

(Chemical Equation Presented) The first total synthesis of a molecule possessing the stereochemistry proposed for onchidin is described. The structure synthesized appears to be different from that of the marine natural product.

N-METHYL AMINO ACIDS

The present invention relates to a compound of formula (I) or (II), processes for preparing them, peptides including them and kits involving them.

THIAZOLIDINE DERIVATIVE AND MEDICINAL USE THEREOF

A thiazolidine derivative represented by the formula (I) wherein each symbol is as defined in the specification, and a pharmaceutically acceptable salt thereof exhibit a potent DPP-IV inhibitory activity, and can be provided as an agent for the prophylaxis or treatment of diabetes, an agent for the prophylaxis or treatment of obesity and the like.

Stereospecific synthesis of the anaesthetic levobupivacaine

Enantiomerically pure (S)-bupivacaine is synthesized from the chiral pool using cheap and readily available (S)-lysine. The key steps in this efficient synthesis include an oxidative de-amination and stereospecific ring closure to form the pipecolamide core structure.