52240-15-0

Upstream product

• 71-43-2 benzene 
• 6328-00-3 4-(3-nitro-phenyl)-4-oxo-butyric acid 
• 2051-95-8 succinylbenzene 

Downstream Products

• 50741-77-0 4-(3-amino-phenyl)-4-oxo-butyric acid ethyl ester 
• 56872-07-2 4-(3-hydroxy-phenyl)-4-oxo-butyric acid 
• 218300-35-7 4-oxo-4-(3-ureido-phenyl)-butyric acid 
• 1304095-39-3 C₁₂H₁₃N₃O 
• 1304095-42-8 C₁₇H₁₅N₃O₂ 
• 1304095-43-9 C₁₈H₁₇N₃O₂ 
• 1304095-44-0 C₁₇H₁₅N₃O 
• 1304095-45-1 C₁₈H₁₇N₃O₃ 
• 1304095-47-3 C₁₅H₁₃N₃O₂ 
• 1304095-50-8 C₁₈H₁₇N₃O₂ 
• 1304095-52-0 C₁₉H₂₀N₄O 
• 1304095-53-1 C₁₇H₁₅N₃O₂ 
• 21282-91-7 6-(3'-amino phenyl)-2,3,4,5-tetrahydro pyridazin-3-one 
• 24743-11-1 4-(m-methoxyphenyl)butanoic acid 

Relevant academic research and scientific papers

Synthesis of different substituted pyridazinone derivatives and their anticonvulsant activity

6-Phenyl(3'-imino-benzylidene)-2,3,4,5-tetrahydro pyridazin-3-one derivatives were synthesized from 6-(3'-aminophenyl)-2,3,4,5-tetrahydro pyridazin-3-one by reaction with different aldehydes. The respective pyridazinone was prepared by cyclization of appropriate β-(aminophenyl) propionic acid with hydrazine hydrate. The pyridazinone derivatives were tested for anticonvulsant activity by MES (maximal electro shock) method and found that few of them have shown significant anticonvulsant activity.

Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain

We have designed and synthesized a (3-aminomethyl-phenyl)-urea scaffold to mimic the X+1-Asn part of the minimal phosphopeptide sequence, Ac-pTyr- X+1-Asn-NH2, recognized by the Grb2SH2 domain. The resulting compounds show the same d