5236-60-2Relevant academic research and scientific papers
Synthesis of 4-thiouracil KPGEPGPK analogues as potential TIIICBP identification tools
Pires, Viviane Silva,Da Nascimento, Sophie,Sonnet, Pascal
experimental part, p. 257 - 266 (2011/10/09)
In this paper, we described the synthesis of three octapeptides analogues which are obtained by the incorporation of photochemical 4-thiouracil (s 4U) probes selectively activables. This probe has been incorporated at the 1 and/or 3 positions in KPGEPGPK sequence since it has been demonstrated that those positions could be mutated without major anti-thrombotic activity modifications. These analogues could be used to identify a new receptor for type III collagen named Type III Collagen Binding Protein (TIIICBP).
A convenient, high-yield synthesis of 1-substituted uracil and thymine derivatives
Rejman, Dominik,Kova?ková, Soňa,Pohl, Radek,Dra?ínsky, Martin,Fiedler, Pavel,Rosenberg, Ivan
experimental part, p. 8513 - 8523 (2010/01/06)
Novel reagents for the synthesis of 1-substituted uracil and thymine derivatives have been developed. The aminolysis of 2- or 4-nitrophenyl 3-ethoxyacryloylcarbamate and 3-ethoxy-2-methylacryloylcarbamate with a variety of primary amino derivatives procee
