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2-[(p-aminophenyl)sulphonyl]ethanol, also known as APSE, is a chemical compound belonging to the sulfonamide class. It features a sulphonamide group attached to a phenyl ring, which is connected to an ethyl chain, making it a versatile chemical for various synthetic purposes in the pharmaceutical and chemical industries.

5246-58-2

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5246-58-2 Usage

Uses

Used in Organic Synthesis:
2-[(p-aminophenyl)sulphonyl]ethanol is used as a reagent in organic synthesis for its ability to facilitate the formation of various organic compounds.
Used in Pharmaceutical Production:
APSE is used as an intermediate in the production of pharmaceuticals, contributing to the synthesis of drugs and other medicinal compounds.
Used in Pesticide Production:
2-[(p-aminophenyl)sulphonyl]ethanol is used as a key ingredient in the production of certain pesticides, highlighting its utility in agricultural chemistry.
Used in Anti-inflammatory and Analgesic Drug Development:
In the pharmaceutical industry, 2-[(p-aminophenyl)sulphonyl]ethanol is studied for its potential therapeutic applications, particularly as an anti-inflammatory and analgesic agent, due to its chemical properties that may contribute to these medicinal effects.

Check Digit Verification of cas no

The CAS Registry Mumber 5246-58-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,4 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5246-58:
(6*5)+(5*2)+(4*4)+(3*6)+(2*5)+(1*8)=92
92 % 10 = 2
So 5246-58-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO3S/c9-7-1-3-8(4-2-7)13(11,12)6-5-10/h1-4,10H,5-6,9H2

5246-58-2Relevant academic research and scientific papers

Preparing methods of p-aminophenyl-beta-hydroxyethylsulfonyl and p-minophenyl-beta-hydroxyethylsulfonyl sulphonate

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Paragraph 0075-0080; 0099; 0103; 0105; 0109; 0111; 0115, (2018/06/21)

The invention relates to preparing methods of p-aminophenyl-beta-hydroxyethylsulfonyl and p-minophenyl-beta-hydroxyethylsulfonyl sulphonate. The preparing methods both comprise the steps that p-aminophenyl-beta-hydroxyethylsulfonyl and hydrogen are used as raw materials, modified framework nickel is used as a hydrogen-adding catalyst, a catalytic hydrogenation reaction is conducted in a solvent toobtain reduction liquid, and modified framework nickel and the solvent in the reduction liquid are separated and removed to obtain p-minophenyl-beta-hydroxyethylsulfonyl sulphonate; according to modified framework nickel, nickel is used as a framework, and modified framework nickel is prepared from, by mass, 75-95 parts of Ni, 3-15 parts of Al and 2-10 parts of metal adjuvant; the metal adjuvantcomprises the combination of any one or at least two of Mo, Cu and Cr. The yield can reach 94% or above; preparation of p-minophenyl-beta-hydroxyethylsulfonyl sulphonate is a continuous production technology, the technology is simplified, the production efficiency is high, the quality is stable, the production cost is low, and the economic benefit and social benefit are obvious.

Dye compounds and resin composition for color filter comprising the same

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Paragraph 0223-0226; 0257-0260, (2016/10/08)

The present invention relates to a pyridone azo dye compound for a color filter resin composition having excellent solubility and heat resistance, which is represented by the following chemical formula 1 and contains an acrylic group or a meta-acrylic group. The pyridone azo dye compound according to the present invention has excellent solubility and heat resistance with respect to an organic solvent, thereby having higher solubility as a coloring agent of the color filter resin composition than a pigment; and maximizing coloring performance and realizing high color reproducibility by reducing an amount of an additive added for pigment dispersion stability. [Chemical formula 1]COPYRIGHT KIPO 2016

(R)-3-(N,N-DIMETHYLAMINO)PYRROLIDINE DERIVATIVES

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Page/Page column 72, (2010/04/27)

(R)-3-(N,N-Dimethyiamino)pyrrolidine derivatives of formula (I), wherein the meaning for Cy1 is as disclosed in the description. These compounds are useful as JAK3 kinase inhibitors

Synthesis and second-order nonlinearities of chiral prolinol-substituted chromophores

Chou, Shang-Shing P.,Yu, Chiung-Yi,Lin, Hong-Cheu,Yang, Pao-Keng

, p. 487 - 492 (2007/10/03)

A new series of thiophene- and furan-containing chromophores with a chiral prolinol donor and a sulfone acceptor has been synthesized. The UV-vis absorptions, second-order nonlinear optical properties, and X-ray crystal structures are described.

Process for producing aminophenyl-β-hydroxyethylsulfone

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, (2008/06/13)

A process for producing aminophenyl-β-hydroxyethylsulfone of the formula (I), STR1 which comprises the following steps: (1) condensing nitrohalobenzene with mercaptoethanol in the presence of an alkali hydroxide and at least one reaction medium selected from N-alkyl-substituted amides and sulfoxides to produce mononitrophenyl-β-hydroxyethylsulfide of the formula (II): STR2 (2) oxidizing the mononitrophenyl-β-hydroxyethylsulfide (II) to produce mononitrophenyl-β-hydroxyethylsulfone of the formula (III): STR3 and (3) reducing the mononitrophenyl-β-hydroxyethylsulfone to produce the aminophenyl-β-hydroxyethylsulfone of the formula (I). This compound is useful as an intermediate for aminophenyl-β-sulfatoethylsulfone represented by the following formula: STR4 which is an important intermediate for vinyl sulfone type reactive dyes largely used for dyeing cellulose fiber materials.

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