52460-99-8

Upstream product

• 1013-88-3 Benzophenone imine 
• 74-90-8 hydrogen cyanide 
• 460-19-5 ethanedinitrile 
• 51065-40-8 α-azidodiphenylacetonitrile 
• 71-43-2 benzene 
• 107783-08-4 α-Diphenylmethylenamino-diphenyl-essigsaeure-nitril 
• 64-17-5 ethanol 
• 119-61-9 benzophenone 
• 143-33-9 sodium cyanide 
• 525-06-4 diphenyl ketene 
• 86-29-3 Diphenylacetonitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 52460-85-2 α-bromo-α-phenylbenzeneacetonitrile 

Downstream Products

• 38093-52-6 acetylamino-diphenyl-acetonitrile 
• 53941-54-1 [2-(2-Benzyloxycarbonylamino-2,2-diphenyl-acetylamino)-2,2-diphenyl-acetylamino]-diphenyl-acetic acid 
• 3060-50-2 2,2-diphenylglycine 
• 90155-46-7 1R,2R-trans-diphenyl-1,2-ethanediamine 

Relevant academic research and scientific papers

Synthesis method and application of six-phenyl trisiloxane epoxy cyclic ether

The method comprises the following steps: synthesizing diphenyl dichlorosilane I through a synthesis method of the following unit cell parameter and the chemical structural formula (1 mmol). The method is characterized in that diphenyldichlorosilane is ad

Preparation and use of ethylenediamine copper perchlorate complex

A kind of ethylenediamine copper perchlorate complex (I), the structural formula of which is as follows: Synthesis method of the ethylenediamine copper perchlorate complex (I), It is weighed 0.710g of ethylenediamine into a 100mL round bottom flask, added

Synthesis method and application of 2-hydroxyphenyl-5-pyrazinyl ketone

A synthesis method of 2-hydroxyphenyl-5-pyrazinyl ketone as shown in the following chemical formula (I) comprises the following steps of: weighing 0.048 g of a palladium complex, 0.8413 g of chromane-3-formaldehyde and 2.5719 g of ammonium formate and put

One-pot synthesis and biological and catalytic applications of organometallic complexes involving oxazolines and (R)/(S)-a-phenylethylamine

The crystal structures of zinc complexes 1 and 3 were determined following synthesis via a one-pot method involving the reaction of 2-hydro-6-methyl-nicotinonitrile and 2-cyanopyridine with different l-amino alcohols mediated by 120–130?mol% ZnCl2/s

Application of chiral oxazoline-copper complex

An application of a bis{2-[4(R)-phenyl-4,5-dihydro]-2-oxazoline}phenol-copper complex with a chemical formula shown in the description is characterized in that the complex has a good catalysis performance when used as a catalyst for a reaction of diphenyl

Synthesis method and applications of pyridine derivative

The invention relates to a synthesis method of 4-phenyl-2-amino-6-alkoxy (methoxy or ethoxy)-3,5-dicyanopyridine. The synthesis method comprises the following steps: putting 0.61668 g of benzylidene malononitrile into a 100 mL round-bottom flask; adding 5

Synthesis method and application of 4, 5-diphenylimidazoline

A synthesis method of a chiral compound with a structural formula shown in the specification comprises synthesis, separation and purification. The synthesis is achieved through the following steps: under anhydrous and anaerobic conditions, using 1 mol% of a catalyst palladium complex as a catalyst, weighing 0.5 mmol of azobenzoyl and 5.0 g of ammonium formate, putting the obtained mixture into a 250mL two-neck flask, adding 100 mL of chlorobenzene as a solvent, carrying out a reflux reaction for 30 hours, carrying out column chromatography separation, eluting by using petroleum ether/dichloromethane (1/100), and naturally volatilizing the collected final component point to obtain the monocrystal 4, 5-diphenylimidazoline. The application of the chiral compound (I) shows a certain catalyticeffect in the reaction of benzophenone imine and trimethylsilyl cyanide, and the conversion rate reaches 66%.

TITANIUM COMPOUNDS AND PROCESS FOR CYANATION OF IMINES

The present invention relates to titanium catalysts for synthesis reactions produced by bringing a reaction mixture comprising a titanium alkoxide and a ligand in contact with water, wherein the ligand is represented by the general formula (e): wherein R

Discovery of substituted 2,4,4-triarylimidazoline derivatives as potent and selective neuropeptide Y Y5 receptor antagonists

Novel imidazoline derivatives were discovered to be potent neuropeptide Y Y5 receptor antagonists. High-throughput screening of Merck sample collections against the human Y5 receptor resulted in the identification of 2,4,4-triphenylimidazoline (1), which had an IC50 of 54 nM. Subsequent optimization led to the identification of several potent derivatives.

Versatile synthesis of free and N-benzyloxycarbonyl-protected 2,2-disubstituted taurines

An effective and versatile method was developed to synthesize N-benzyloxycarbonyl-protected and free 2,2-disubstituted taurines. Several novel 2,2-disubstituted taurines, including aliphatic/aromatic and cyclic/acyclic derivatives, were obtained, which demonstrates the generality of this method. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.