52509-81-6

Basic information

• Product Name: 4-ANISIC ACID POTASSIUM SALT
• Synonyms: POTASSIUM 4-ANISATE;4-ANISIC ACID POTASSIUM SALT;4-METHOXYBENZOIC ACID POTASSIUM SALT;potassium p-anisate;p-Anisic acid potassium salt
• CAS NO: 52509-81-6
• Molecular Formula: C₈H₇O₃*K
• Molecular Weight: 190.24
• EINECS: 257-978-9
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 52509-81-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 211.6°Cat760mmHg
• Flash Point: 84.2°C
• Appearance: /
• Density: 0.94g/cm³
• Vapor Pressure: 0.00206mmHg at 25°C
• CAS DataBase Reference: 4-ANISIC ACID POTASSIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ANISIC ACID POTASSIUM SALT(52509-81-6)
• EPA Substance Registry System: 4-ANISIC ACID POTASSIUM SALT(52509-81-6)

Safety Data

• Hazardous Substances Data: 52509-81-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8O3.K/c1-11-7-4-2-6(3-5-7)8(9)10;/h2-5H,1H3,(H,9,10);/q;+1/p-1

Upstream product

• 105-13-5 4-Methoxybenzyl alcohol 
• 100-09-4 4-methoxybenzoic acid 
• 121-98-2 methyl 4-methoxybenzoate 

Downstream Products

• 76241-05-9 (4-methoxybenzoyloxymethyl)triethoxysilane 
• 55153-14-5 2-(4-methoxybenzoyloxy)-1-phenylethanone 
• 100-09-4 4-methoxybenzoic acid 
• 121-98-2 methyl 4-methoxybenzoate 
• 151-10-0 1,3-Dimethoxybenzene 
• 25783-45-3 1-ethoxy-3-methoxybenzene 
• 51241-30-6 1-methoxy-3-propoxybenzene 
• 51241-41-9 m-methoxyphenyl i-propyl ether 
• 21144-16-1 3-benzyloxyanisole 
• 6488-05-7 2-[2-(3-methoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione 
• 7472-54-0 N-(p-methoxyphenyl)benzamide 
• 488713-19-5 (E)-2-(4-methoxy-phenyl)-but-2-enedioic acid dimethyl ester 
• 124408-68-0 dimethyl 2-(4-methoxyphenyl)maleate 
• 19048-04-5 Bis-<4-methoxy-benzoesaeure>-oxalsaeure-anhydrid 

Relevant articles and documents

An Anionic, Chelating C(sp3)/NHC ligand from the Combination of an N-heterobicyclic Carbene and Barbituric Heterocycle

The coordination chemistry of the anionic NHC1-based on an imidazo[1,5-a]pyridin-3-ylidene (IPy) platform substituted at the C5 position by an anionic barbituric heterocycle was studied with d6(Ru(II), Mn(I)) and d8(Pd(II), Rh(I), Ir(I), Au(III)) transition-metal centers. While the anionic barbituric heterocycle is planar in the zwitterionic NHC precursor 1·H, NMR spectroscopic analyses supplemented by X-ray diffraction studies evidenced the chelating behavior of ligand 1-through the carbenic and the malonic carbon atoms in all of the complexes, resulting from a deformation of the lateral barbituric heterocycle. The complexes were obtained by reaction of the free carbene with the appropriate metal precursor, except for the Au(III) complex 10, which was obtained by oxidation of the antecedent gold(I) complex [AuCl(1)]?with PhICl2as an external oxidant. During the course of the process, the kinetic gold(I) intermediate 9 resulting from the oxidation of the malonic carbon of the barbituric moiety was isolated upon crystallization from the reaction mixture. The νCOstretching frequencies recorded for complex [Rh(1)(CO)2] (5) demonstrated the strong donating character of the malonate-C(sp3)/NHC ligand 1-. The ruthenium complex [Ru(1)Cl(p-cymene)] (11) was implemented as a precatalyst in the dehydrogenative synthesis of carboxylic acid derivatives from primary alcohols and exhibited high activities at low catalyst loadings (25-250 ppm) and a large tolerance toward functional groups.

Synthesis of aryl ethers from benzoates through carboxylate-directed C-H-activating alkoxylation with concomitant protodecarboxylation

One in, one out: In the presence of a copper/silver bimetallic catalyst system, aromatic carboxylate salts undergo ortho C-H alkoxylation with concomitant loss of the carboxylate directing group in a protodecarboxylation step (see scheme, FG=functional group). This process provides a convenient synthetic access to the important class of aromatic ethers from widely available carboxylic acids. Copyright