52535-76-9

Usage

Chemical class

Benzo[b]thiophene carboxylic acids

Molecular structure

Contains a 4-chloro-benzoylamino group and a tetrahydro-benzo[b]thiophene-3-carboxylic acid moiety

Potential applications

Medicine, specifically in the development of pharmaceutical drugs

Further research

Necessary to fully understand the properties and potential uses of 2-(4-chloro-benzoylamino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid

Upstream product

• 74-11-3 para-chlorobenzoic acid 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 122-01-0 4-chloro-benzoyl chloride 
• 52535-71-4 2-(4-chloro)benzamide-6-ethyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester 

Downstream Products

• 52535-78-1 4-chloro-N-(4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl)-benzamide 

Relevant academic research and scientific papers

Preparation method and application of tetrahydrobenzothiophene compound and pharmaceutical composition

The invention belongs to the field of medicines, and particularly relates to a tetrahydrobenzothiophene compound as well as a pharmaceutical composition and a preparation method and application thereof. The tetrahydrobenzothiophene compound is a compound I as shown I. In-flight R1 And R2 The C1 -4 is a saturated/unsaturated hydrocarbon group. - OCH3 , OCH2 CH3 Phenyl, substituted phenyl, NO2 One - COR of - OH - F, Cl - Br. I - H R1 AND R2 Or different. R3 It is-F. - Cl, Br, I, OH, Amino, C1 -4 saturated/unsaturated hydrocarbon group, OCH3 , OCH2 CH3 , H, Wherein one of them is, n ≥ 5, n Being an integer. The compound effectively inhibits salmonella by inhibiting the synthesis of ATP-dependent transporter in the lipopolysaccharide synthesis pathway. Aeruginosa, escherichia coli and staphylococcus aureus.