52626-59-2Relevant academic research and scientific papers
Compounds, composition, and methods for photodynamic therapy
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Page column 35; sheet 9, (2008/06/13)
Disclosed are novel compounds, compositions, and methods that are particularly useful in photodynamic therapy. In particular, the inventive compounds, compositions, and methods relate to the formation of cytotoxic radical species in the presence of light. Significantly, the compounds, compositions, and methods of the present invention do not require the presence of oxygen in the photodynamic therapy and, as such, rely on a unimolecular mechanism for producing the radicals. The inventive compounds, compositions, and methods can be used, for example, in the treatment of cancers as well as infections caused by microorganisms such as protozoa, fungi, bacteria, and viruses.
Star-porphyrazines: Synthetic, structural, and spectral investigation of complexes of the polynucleating porphyrazineoctathiolato ligand
Velázquez, Christopher S.,Fox, Glenn A.,Broderick, William E.,Andersen, Kevin A.,Anderson, Oren P.,Barrett, Anthony G. M.,Huffman, Brian M.
, p. 7416 - 7424 (2007/10/02)
We have devised a new polynucleating porphyrinic ligand, porphyrazine-2,3,7,8,12,13,17,18-octathiolato, (pz)(S-)8, the molecular structure of which may be thought of as a porphyrazine (tetraazaporphyrin) with four dithiolene moieties
