5466-54-6Relevant articles and documents
An Alternative Synthesis of Sodium Cyanodithioformate and the Disodium Salt of cis-1,2-Dicyanoethylene-1,2-dithiol
Hoepping, Alexander,Mengel, Rudolf,Mayer, Roland
, p. 269 - 270 (1998)
A new synthesis of sodium cyanodithioformate 1 and the disodium salt of cis-1,2-dicyanoethylene-1,2-dithiol 2 is reported. The key step involves a nucleophilic thiolation with elemental sulfur starting from a substituted acetonitrile 4. This method may serve as a cyanide- and carbondisulfide-free alternative in the preparation of the title compounds.
Compounds, composition, and methods for photodynamic therapy
-
Page column 35, (2008/06/13)
Disclosed are novel compounds, compositions, and methods that are particularly useful in photodynamic therapy. In particular, the inventive compounds, compositions, and methods relate to the formation of cytotoxic radical species in the presence of light. Significantly, the compounds, compositions, and methods of the present invention do not require the presence of oxygen in the photodynamic therapy and, as such, rely on a unimolecular mechanism for producing the radicals. The inventive compounds, compositions, and methods can be used, for example, in the treatment of cancers as well as infections caused by microorganisms such as protozoa, fungi, bacteria, and viruses.
Methoxy derivatives of 1,4-dithiepino-[2,3-c]-pyrrole
-
, (2008/06/13)
Compounds of the formula: STR1 wherein A represents pyrid-2-yl, quinol-2-yl or 1,8-naphthyridin-2-yl, each such radical being optionally substituted by a halogen atom, or an alkyl or alkoxy radical of 1 through 4 carbon atoms, and R represents hydrogen, an alkyl radical of 1 through 4 carbon atoms, an alkenyl radical of 2 through 4 carbon atoms or an alkanoyl radical of 1 through 4 carbon atoms, are new compounds possessing pharmacological properties. They are particularly active as tranquillizers, anti-convulsants, decontracturants and hypnogenic agents.