52829-72-8

Upstream product

• 75-15-0 carbon disulfide 
• 2450-71-7 Propargylamine 
• 15430-52-1 prop-2-yn-1-amine hydrochloride 

Downstream Products

• 17626-82-3 5-methyl-3H-thiazole-2-thione 
• 33342-65-3 2-chloro-5-methyl-thiazole 
• 285135-53-7 5-Methyl-thiazole-2-sulfonic acid amide 
• 105827-91-6 α-Cl-β-thiazolyl chloride 
• 192439-49-9 2-benzylmercapto-5-methylenethiazoline 
• 95927-09-6 (Diphenyl)thiocarbamidsaeure-S-(5-methyl-1,3-thiazol-2-yl)ester 
• 95927-06-3 5-Methylen-3-(4-nitrobenzoyl)-1,3-thiazolidin-2-thion 
• 95927-05-2 3-Benzoyl-5-methylen-1,3-thiazolidin-2-thion 
• 95963-05-6 2-Benzylthio-5-methyl-1,3-thiazol 
• 140652-68-2 2-(3-Benzyliden-2-phenyl-carbazoylthio)-5-methyl-thiazol 

Relevant academic research and scientific papers

A concise synthesis of substituted thiourea derivatives in aqueous medium

(Figure Presented) An efficient method for the synthesis of symmetrical and unsymmetrical substituted thiourea derivatives by means of simple condensation between available building blocks such as amines and carbon disulfide in aqueous medium is presented. This protocol works smoothly with aliphatic primary amines to afford various di- and trisubstituted thiourea derivatives. The present method is also useful in synthesizing various substituted 2-mercapto imidazole heterocycles. This method proceeds through a xanthate (amino dithiol deivative) intermediate, unlike isothiocyanate as in an earlier known method.

A convenient method for the synthesis of substituted thioureas

A convenient method for the synthesis of substituted thioureas by the reaction of primary amines with molybdenum dialkyl dithiocarbamates has been developed. Primary amines on reaction with 0.5 equiv of molybdenum xanthate produce the corresponding thiour

Transition-metal-catalyzed reactions of propargylamine with carbon dioxide and carbon disulfide

The reactions of propargylamine derivatives with carbon dioxide and carbon disulfide have been systematically examined in the presence of transition-metal catalysts. Pd(OAc)2 is the best catalyst for the formation of the corresponding oxazolidinones. In addition, we found that, in the reaction of propargylamine with carbon dioxide catalyzed by palladium (0) metal catalyst in toluene, both oxazolidinone 1 and imidazolidinone 2 could be obtained under mild reaction conditions at the same time. The reaction of 1 with primary and secondary amines has been examined. A plausible reaction mechanism for the formation of 2 was proposed. In addition, in this paper, we first disclosed the ligand's effect on this reaction. Using PBut3 as a ligand with Pd2(dba)3, 1 was exclusively formed in 90% yield.

Reactions of 5-methylene-1,3-thiazolidine-2-thione and 5-methylene-2-oxazolidinone with isocyanates catalyzed by bases

5-Methylene-1,3-thiazolidine-2-thione and 5-methylene-2-oxazolidinone can react with isocyanates to give the corresponding condensed urethanes in high yields in the presence of organic or inorganic bases under mild reaction conditions.

Synthetic approaches towards CGA 293'343: A novel broad-spectrum insecticide

Synthetic approaches towards CGA 293'343 (ISO draft common name: thiamethoxam), a novel broad-spectrum insecticide from the class neonicotinoids, are described. 2-Chloro-5-chloromethylthiazole, an important synthetic intermediate, was prepared from five different precursors. Alternatively, CGA 293'343 was prepared via the intermediate 2-benzylmercapto-5-chloromethylthiazole, the synthesis of which is also described.

Alkylation, Acylation, and Carbamoylation Products of 5-Methylene-1,3-thiazolidine-2-thione

The reaction product of prop-2-inylamine and carbon disulfide was contrary to earlier results identified as 5-methylene-1,3-thiazolidine-2-thione (3a).This was reacted with alkyl halides, acyl, carbamoyl, and thiocarbamoyl chlorides.The structures of the