52867-49-9

Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-(phenylmethyl)-, methyl ester is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-(phenylmethyl)-, methyl ester is utilized as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides. Its diverse chemical functionalities enable the creation of novel compounds with improved efficacy and selectivity.
Used in Materials Science:
1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-(phenylmethyl)-, methyl ester is employed as a building block in the development of new materials with unique properties. Its versatile structure allows for the synthesis of materials with potential applications in various fields, such as electronics, coatings, and adhesives.
Further research and development of 1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-(phenylmethyl)-, methyl ester could lead to the discovery of new drugs, agrochemicals, and materials with interesting properties and potential applications in various industries.

Upstream product

• 1073-62-7 N-benzylhydrazine hydrochloride 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 86625-25-4 methyl 3-hydroxy-1H-pyrazole-5-carboxylate 
• 100-39-0 benzyl bromide 
• 40711-33-9 5-hydroxy-2H-pyrazole-3-carboxylic acid ethyl ester 

Downstream Products

• 268726-62-1 1-benzyl-3-(3-dimethylaminopropyloxy)-5-methoxycarbonyl-1H-pyrazole 
• 268725-61-7 1-benzyl-3-(3-di-methylaminopropyloxy)-1H-pyrazole-5-carboxylic acid 

Relevant academic research and scientific papers

ARYLALKANOIC ACID DERIVATIVE

A compound represented by the formula (I): wherein Ar is an optionally substituted aromatic ring; Xa, Xc, Ya, Yc, Z1 and Z2 are each a bond, O, S, -CO-, -CS-, - CR3 (OR4) -, -NR5-, -SO-, -SO2-, -CONR6- or -NR6CO- (wherein R3, R4, R5 and R6 are as defined in the specification); Xb and Yb are each a bond or a divalent hydrocarbon group having 1 to 20 carbon atoms; R1 is an optionally substituted hydrocarbon group; ring A is an optionally further substituted aromatic ring, provided that the ring should not be benzimidazole; n is an integer of 1 to 8; ring B is an optionally further substituted aromatic ring, provided that the ring should not be oxazole; W is a divalent saturated hydrocarbon group having 1 to 20 carbon atoms; and R2 is -OR8 or -NR9R10 (wherein R8, R9 and R10 are as defined in the specification) or a salt thereof, is useful as an agent for the prophylaxis or treatment of diabetes and the like.

ARYLALKANOIC ACID DERIVATIVE

A compound represented by the general formula (I): [wherein Ar represents an optionally substituted aromatic ring; Xa, Xc, Ya, Yc, Z1, and Z2 each represents a bond, O, S, -CO-, -CS-, -CR3(OR4)-, -NR5-, -SO-, -SO2-, -CONR6-, or -NR6CO- (R3, R4, R5, and R6 are as defined in the description); Xb and Yb each represents a bond or a C1-20 divalent hydrocarbon group; R1 represents an optionally substituted hydrocarbon group; ring A represents an aromatic ring (other than benzimidazole) which may be further substituted; n is an integer of 1-8; ring B represents an aromatic ring (other than oxazole) which may be further substituted; W represents a C1-20 divalent saturated hydrocarbon group; and R2 represents -OR8 or -NR9R10 (R8, R9, and R10 are as defined in the description)] or a salt of the compound. It is useful as a preventive/therapeutic agent for diabetes, etc.

Benzimidazole derivatives and their use as KDR kinase protein inhibitors

The invention discloses and claims benzimidazole compounds of formula (I): wherein X is C—R2; Y is C—R2 or C—R3; W and Z are each C—R3; R1 is an optionally substituted aryl, heteroaryl or a saturated 5- or 6-membered monocyclic heterocyclic radical or a b